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Selleck Chemicals LLC

4576

Basic Information

Company Name:Selleck Chemicals LLC

Business Type:Chemical manufacturer

Total NO.Employees:

Country/Region:USA

Certificates:

Year Established:

Introduction of Selleck Chemicals LLC

Selleck Chemicals supplies over 3,000 inhibitors used in the study of cell signaling pathways. We actively tracks the latest science so our customers can rely on us to be the leading supplier of the newest inhibitors.

Web: www.selleckchem.com TEL:+1-832-582-8158 Fax:+1-832-582-8590 Email:[email protected]

Products of Selleck Chemicals LLC

  • Chemical Name: LY2857785
    CAS No.: 1619903-54-6 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: LY 2857785;LY-2857785; (1r,... Quality Control & MSDS Files:
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    Brief introduction:

    LY2857785 is a type I reversible and competitive ATP kinase inhibitor against <b>CDK9</b>(IC50=0.011 μM) and also inhibits other transcription kinases <b>CDK8</b>(IC50=0.016 μM) and <b>CDK7</b> (IC50=0.246 μM).

  • Chemical Name: Etomoxir
    CAS No.: 828934-41-4 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: (+)-Etomoxir sodium salt; s... Quality Control & MSDS Files:
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    Brief introduction:

    Etomoxir is an irreversible inhibitor of <b>carnitine palmitoyltransferase-1 (CPT-1)</b> on the outer face of the inner mitochondrial membrane.

  • Chemical Name: IM-12
    CAS No.: 1129669-05-1 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: IM 12;IM12; 3-((4-fluorophe... Quality Control & MSDS Files:
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    Brief introduction:

    IM-12 is a selective <b>GSK-3β</b> inhibitor with <b>IC50</b> of 53 nM, and also enhances canonical Wnt signalling.

  • Chemical Name: Nexturastat A
    CAS No.: 1403783-31-2 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: 4-((1-butyl-3-phenylureido)... Quality Control & MSDS Files:
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    Brief introduction:

    Nexturastat A is a potent and selective <b>HDAC6</b> inhibitor with <b>IC50</b> of 5 nM, &gt;190-fold selectivity over other HDACs.

  • Chemical Name: 4SC-202
    CAS No.: 910462-43-0 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: 4SC 202 free base;4SC202 fr... Quality Control & MSDS Files:
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    Brief introduction:

    4SC-202 is a selective class I <b>HDAC</b> inhibitor with <b>IC50</b> of 1.20 μM, 1.12 μM, and 0.57 μM for HDAC1, HDAC2, and HDAC3, respectively. Also displays inhibitory activity against <b>Lysine specific demethylase 1 (LSD1)</b>. Phase 1.

  • Chemical Name: Defactinib
    CAS No.: 1073154-85-4 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: VS-6063;VS6063;VS 6063; N-m... Quality Control & MSDS Files:
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    Brief introduction:

    Defactinib (VS-6063, PF-04554878) is a selective, and orally active <b>FAK</b> inhibitor. Phase 2.

  • Chemical Name: Ozanimod
    CAS No.: 1306760-87-1 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: RPC-1063 Quality Control & MSDS Files:
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    Brief introduction:

    Ozanimod (RPC1063) is a selective oral <b>S1P Receptor 1</b> modulator. Phase 3.

  • Chemical Name: YH239-EE
    CAS No.: 1364488-67-4 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: YH 239-EE;YH 239 EE; ethyl ... Quality Control & MSDS Files:
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    Brief introduction:

    YH239-EE, the ethyl ester of YH239, is a potent <b>p53-MDM2</b> antagonist and an <b>apoptosis</b> inducer.

  • Chemical Name: PI-1840
    CAS No.: 1401223-22-0 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: PI 1840;PI1840; N-isopropyl... Quality Control & MSDS Files:
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    Brief introduction:

    PI-1840 is a reversible and selective <b>chymotrypsin-like (CT-L)</b> inhibitor with <b>IC50</b> of 27 nM with little effects on the other two major proteasome proteolytic activities, trypsin-like (T-L) and postglutamyl-peptide-hydrolysis-like (PGPH-L).

  • Chemical Name: Uracil
    CAS No.: 66-22-8 Purity: Appearances:
    Brand: Synonyms: 2,4(1H,3H)-Pyrimidinedione;... Quality Control & MSDS Files:
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    Brief introduction:

    Uracil is one of the four nucleobases in the nucleic acid of RNA that are represented by the letters A, G, C and U. The others are adenine (A), cytosine (C), and guanine (G). In RNA, uracil binds to adenine via two hydrogen bonds. In DNA, the uracil nucleobase is replaced by thymine. Uracil is a demethylated form of thymine. Uracil's u...

  • Chemical Name: Buparvaquone
    CAS No.: 88426-33-9 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: Butalex; 2-((4-(tert-butyl)... Quality Control & MSDS Files:
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    Brief introduction:

    1,​4-​Naphthalenedione, 2-​[[4-​(1,​1-​dimethylethyl)​cyclohexyl]​methyl]​-​3-​hydroxy-

  • Chemical Name: Serabelisib
    CAS No.: 1268454-23-4 Purity: Appearances: White to gray Solid
    Brand: Synonyms: Serabelisib;INK1117 Quality Control & MSDS Files:
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    Brief introduction:

    Serabelisib (INK-1117,MLN-1117,TAK-117) is a potent and selective oral <b>PI3Kα</b> isoform inhibitor (<b>IC50</b> of 21 nmol/L against PI3Kα) that has demonstrated &gt; 100-fold selectivity relative to other class I PI3K family members (PI3Kβ/γ/δ) and mTOR, and a high degree of selectivity against many other kinase.

  • Chemical Name: Liothyronine Sodium
    CAS No.: 55-06-1 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: T3 Sodium salt;Sodium L-3,3... Quality Control & MSDS Files:
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    Brief introduction:

    Liothyronine Sodium is the most potent form of thyroid hormone acting on the body to increase the basal metabolic rate, affect protein synthesis.

  • Chemical Name: Saxagliptin hydrate
    CAS No.: 945667-22-1 Purity: Appearances:
    Brand: Synonyms: BMS-477118 hydrate;Onglyza ... Quality Control & MSDS Files:
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    Brief introduction:

    Saxagliptin H2O is a selective and reversible <b>DPP4</b> inhibitor with <b>IC50</b> of 26 nM.

  • Chemical Name: Fidaxomicin
    CAS No.: 873857-62-6 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: OPT-80;PAR-101;Dificid;Difi... Quality Control & MSDS Files:
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    Brief introduction:

    Fidaxomicin is a narrow spectrum macrocyclic antibiotic that inhibits RNA polymerase sigma subunit.

  • Chemical Name: GNE-9605
    CAS No.: 1536200-31-3 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: GNE 9605;GNE9605;N2-(5-chlo... Quality Control & MSDS Files:
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    Brief introduction:

    GNE-9605 is a highly potent and selective <b>leucine-rich repeat kinase 2 (LRRK2)</b> inhibitor with <b>K<sub>i</sub></b> and <b>IC50</b> of 2 nM and 19 nM, respectively.

  • Chemical Name: FPH2
    CAS No.: 957485-64-2 Purity: Appearances:
    Brand: Synonyms: FPH 2;FPH-2;BRD-9424;BRD 94... Quality Control & MSDS Files:
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    Brief introduction:

    FPH2 (BRD-9424) is a small molecule, which promotes differentiation of iPS-derived hepatocytes.

  • Chemical Name: umbralisib
    CAS No.: 1532533-67-7 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: TGR 1202;TGR1202; (S)-2-(1-... Quality Control & MSDS Files:
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    Brief introduction:

    TGR-1202, a novel, next generation <b>PI3Kδ</b> inhibitor, inhibits PI3Kδ activity in enzyme and cell based assays with <b>IC50</b> and <b>EC50</b> values of 22.2 &amp; 24.3 nM, respectively.

  • Chemical Name: Doxylamine Succinate
    CAS No.: 562-10-7 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: N,N-Dimethyl-2-[1-phenyl-1-... Quality Control & MSDS Files:
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    Brief introduction:

    Doxylamine succinate competitively inhibits histamine at <b>H1 receptors</b> with substantial sedative and anticholinergic effects.

  • Chemical Name: K02288
    CAS No.: 1431985-92-0 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: K-02288; K 02288; K 02288. Quality Control & MSDS Files:
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    Brief introduction:

    K02288 is a potent, and selective type I BMP receptor inhibitor with <b>IC50</b> of 1.1, 1.8, 6.4 nM for <b>ALK2</b>, <b>ALK1</b> and <b>ALK6</b>, showing weaker inhibition on other ALKs (3, 4, 5) and ActRIIA.