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Cayman Chemical Company

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Basic Information

Company Name:Cayman Chemical Company

Business Type:Chemical manufacturer

Total NO.Employees:350+ worldwide

Country/Region:USA

Certificates:

Year Established: 1980

Introduction of Cayman Chemical Company

Our mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy. Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination. Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research

Web: www.caymanchem.com TEL:Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 Fax:(734) 971-3640 Email:[email protected]

Products of Cayman Chemical Company

  • Chemical Name: (R)-(+)-Etomoxir (sodium salt)
    CAS No.: 828934-41-4 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: (+)-Etomoxir sodium salt; s... Quality Control & MSDS Files:
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    (R)-(+)-Etomoxir (sodium salt) is a potent inhibitor of carnitine palmitoyltransferase I (CPT1); inhibits β-oxidation in mitochondria; shown to inhibit cardiolipin biosynthesis from exogenous fatty acid in H9c2 cells.

  • Chemical Name: IM-12
    CAS No.: 1129669-05-1 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: IM 12;IM12; 3-((4-fluorophe... Quality Control & MSDS Files:
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  • Chemical Name: Nexturastat A
    CAS No.: 1403783-31-2 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: 4-((1-butyl-3-phenylureido)... Quality Control & MSDS Files:
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    Nexturastat A is a potent and selective HDAC6 inhibitor with IC50 of 5 nM; no inhibition on other HDAC forms. IC50 value: 5 nM [1] Target: HDAC6 inhibitor Nexturastat A displayed low micromolar activity compared to the low nanomolar activity against HDAC6.

  • Chemical Name: Arg-Gly-Asp-Ser
    CAS No.: 91037-65-9 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: RGDS peptide;Fibronectin In... Quality Control & MSDS Files:
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    Arg-Gly-Asp-Ser(RGDS peptide) is an integrin binding sequence that inhibits integrin receptor function; decreases systemic inflammation via inhibition of collagen-triggered activation of leukocytes and attenuates expression of inflammatory cytokines, iNOS and MMP-9.

  • Chemical Name: Defactinib
    CAS No.: 1073154-85-4 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: VS-6063;VS6063;VS 6063; N-m... Quality Control & MSDS Files:
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  • Chemical Name: Liothyronine (sodium)
    CAS No.: 55-06-1 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: 3,3',5-Triiodo-L-thyronine ... Quality Control & MSDS Files:
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    Liothyronine sodium (T3 Sodium sal) is the most potent form of thyroid hormone used to treat hypothyroidism and myxedema coma.

  • Chemical Name: Fidaxomicin
    CAS No.: 873857-62-6 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: OPT-80;PAR-101;Dificid;Difi... Quality Control & MSDS Files:
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    Fidaxomicin(OPT-80; PAR-101) is a new class of narrow spectrum macrocyclic antibiotic drug; selective eradication of pathogenic Clostridium difficile with minimal disruption to the multiple species of bacteria that make up the normal, healthy intestinal flora.

  • Chemical Name: K 02288
    CAS No.: 1431985-92-0 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: K02288;K-02288; 3-(6-amino-... Quality Control & MSDS Files:
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  • Chemical Name: AZ191
    CAS No.: 1594092-37-1 Purity: Appearances: light yellow to khaki Solid
    Brand: Synonyms: AZ 191; N-(2-methoxy-4-(4-m... Quality Control & MSDS Files:
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  • Chemical Name: CID 16020046
    CAS No.: 834903-43-4 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: CID16020046;CID-16020046; 4... Quality Control & MSDS Files:
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    CID 16020046 is a potent and selective GPR55(LPI receptor) antagonist; inhibitsGPR55 constitutive activity with IC50 of 0.15 uM. IC50 value: 0.15 uM [1] Target: GPR55 antagonist In yeast cells expressing human GPR55, CID16020046 antagonized agonist-induced receptor activation.

  • Chemical Name: ISO-1
    CAS No.: 478336-92-4 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: ISO 1;ISO1;MIF Antagonist; ... Quality Control & MSDS Files:
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    ISO-1 is an inhibitor of MIF d-dopachrome tautomerase activity with an IC50 of about 7 uM. IC50 value: 7 uM [1] Target: MIF inhibitor in vitro: ISO-1 inhibited MIF tautomerase activity in a dose-dependent manner with an IC50 of about 7 μM, but the non-hydroxylated phenyl analog (compound 2) was 10–15 times less potent.

  • Chemical Name: AK-7
    CAS No.: 420831-40-9 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: AK 7;AK7; 3-(azepan-1-ylsul... Quality Control & MSDS Files:
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    AK-7 is a selective and brain-permeable SIRT2 inhibitor; is neuroprotective in Huntington disease mouse models. IC50 value: Target: SIRT2 AK-7 treated R6/2 mice performed significantly better than vehicle treated littermates on the accelerating rotarod at 8 and 11 weeks of age.

  • Chemical Name: Eltoprazine (hydrochloride)
    CAS No.: 98206-09-8 Purity: Appearances:
    Brand: Synonyms: DU-28853 hydrochloride;DU28... Quality Control & MSDS Files:
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    Eltoprazine(DU28853) is a serenic or antiaggressive agent which as an agonist at the 5-HT1A and 5-HT1B receptors and as an antagonist at the 5-HT2C receptor. IC50 value: Target: 5-HT1A/1B agonist; 5-HT2C antagonist in vitro: The binding of [3H]eltoprazine to whole tissue sections was saturable and revealed an apparent dissociation c...

  • Chemical Name: FR 180204
    CAS No.: 865362-74-9 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: FR 180204;FR-180204; 5-(2-p... Quality Control & MSDS Files:
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    FR180204 is a potent and selective ATP-competitive inhibitor of ERK1 and ERK2 with Ki value of 0.31 uM and 0.14 uM respectively; has IC50 values of 0.51 and 0.33 μM in enzymatic assays against ERK1 and ERK2, respectively. IC50 value: 0.31 uM/0.14 uM(Ki for ERK1/ERK2); 0.51uM/0.33 μM(ERK1/ERK2) [1] [2] Target: ERK1/2 inhibitor in vi...

  • Chemical Name: ML347
    CAS No.: 1062368-49-3 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: ML 347;ML-347;LDN-193719;LD... Quality Control & MSDS Files:
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    ML347(DN193719) is a highly selective ALK1/ALK2 inhibitor with IC50s of 46/32 nM; shows >300-fold selectivity for ALK2 vs.

  • Chemical Name: PSN632408
    CAS No.: 857652-30-3 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: PSN 632408;PSN-632408; tert... Quality Control & MSDS Files:
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    PSN632408 is an optimized agonist of GPR119 receptors that shows similar potency to OEA at both recombinant mouse and human GPR119 receptors, exhibiting EC50 values of 5.6 and 7.9 uM, respectively. IC50 value: 5.6/7.9 uM ( recombinant mouse/ human GPR119) [1] Target: GPR119 agonist Systemic administration of PSN632408 (30 mg/kgintra...

  • Chemical Name: CFTR(inh)-172
    CAS No.: 307510-92-5 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: CFTR Inhibitor-172;CFTRinh-... Quality Control & MSDS Files:
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    CFTR(inh)-172 is an reversibly inhibitor of CFTR short-circuit current in less than 2 minutes in a voltage-independent manner with Ki approximately 300 nM.

  • Chemical Name: DMH-1
    CAS No.: 1206711-16-1 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: DMH1;DMH 1; 4-(6-(4-isoprop... Quality Control & MSDS Files:
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    DMH-1 is a potent and selective BMP inhibitor with IC50s of 27/107.9/<5 nM for ALK1/2/3 respectively; inactive on ALK5, BMPR2, AMPK and VEGFR2. IC50 value: 27/107.9/<5 nM(ALK1/2/3) [1] Target: ALK inhibitor DMH-1 shows the most selectivity within these three compounds(LDN-193189, DMH-1 and dorsomorphin) [1].

  • Chemical Name: EHT 1864
    CAS No.: 754240-09-0 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: EHT1864;EHT-1864; 2-(morpho... Quality Control & MSDS Files:
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    Brief introduction:

    EHT 1864 is a small molecule inhibitor of Rac1 signaling; modulate γ-Secretase-mediated APP processing. IC50 value: Target: Rac1 inhibitor in vitro: EHT 1864 blocks Aβ 40 and Aβ 42 production but does not impact sAPPα levels and does not inhibit γ-secretase.