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Cayman Chemical Company

11746

Basic Information

Company Name:Cayman Chemical Company

Business Type:Chemical manufacturer

Total NO.Employees:350+ worldwide

Country/Region:USA

Certificates:

Year Established: 1980

Introduction of Cayman Chemical Company

Our mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy. Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination. Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research

Web: www.caymanchem.com TEL:Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 Fax:(734) 971-3640 Email:[email protected]

Products of Cayman Chemical Company

  • Chemical Name: (+)-Etomoxir (sodium salt)
    CAS No.: 828934-41-4 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: (+)-Etomoxir sodium salt; s... Quality Control & MSDS Files:
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    Brief introduction:

    (R)-(+)-Etomoxir (sodium salt) is a potent inhibitor of carnitine palmitoyltransferase I (CPT1); inhibits β-oxidation in mitochondria; shown to inhibit cardiolipin biosynthesis from exogenous fatty acid in H9c2 cells.

  • Chemical Name: IM-12
    CAS No.: 1129669-05-1 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: IM 12;IM12; 3-((4-fluorophe... Quality Control & MSDS Files:
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    IM-12 is an inhibitor of <b>GSK-3β</b>, with an <b>IC<sub>50</sub></b> of 53 nM, and also enhances Wnt signalling.

  • Chemical Name: Nexturastat A
    CAS No.: 1403783-31-2 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: 4-((1-butyl-3-phenylureido)... Quality Control & MSDS Files:
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    Brief introduction:

    Nexturastat A is a potent and selective HDAC6 inhibitor with IC50 of 5 nM; no inhibition on other HDAC forms. IC50 value: 5 nM [1] Target: HDAC6 inhibitor Nexturastat A displayed low micromolar activity compared to the low nanomolar activity against HDAC6.

  • Chemical Name: kb-NB77-78
    CAS No.: 1350622-33-1 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: 9-((tert-butyldimethylsilyl... Quality Control & MSDS Files:
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    Brief introduction:

    kb-NB77-78 is an analog of CID797718, which is a by-product of the synthesis of the parental compound, CID755673(PKD1 inhibitor).

  • Chemical Name: RGDS Peptide
    CAS No.: 91037-65-9 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: RGDS peptide;Fibronectin In... Quality Control & MSDS Files:
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    Arg-Gly-Asp-Ser(RGDS peptide) is an integrin binding sequence that inhibits integrin receptor function; decreases systemic inflammation via inhibition of collagen-triggered activation of leukocytes and attenuates expression of inflammatory cytokines, iNOS and MMP-9.

  • Chemical Name: Defactinib
    CAS No.: 1073154-85-4 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: VS-6063;VS6063;VS 6063; N-m... Quality Control & MSDS Files:
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    Brief introduction:

    Defactinib is a novel <b>FAK</b> inhibitor, which inhibits FAK phosphorylation at the Tyr397 site in a time- and dose-dependent manner.

  • Chemical Name: Ozanimod
    CAS No.: 1306760-87-1 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: RPC-1063 Quality Control & MSDS Files:
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    Brief introduction:

    Ozanimod is a potent and selective <b>S1P<sub>1</sub></b> and <b>S1P<sub>5</sub> receptor</b> agonist with <b>EC<sub>50</sub></b>s of 410±160 pM and 11±4.3 nM in [<sup>35</sup>S]-GTPγS binding, respectively.

  • Chemical Name: Buparvaquone
    CAS No.: 88426-33-9 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: Butalex; 2-((4-(tert-butyl)... Quality Control & MSDS Files:
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    Brief introduction:

    Buparvaquone(Butalex) is a hydroxynaphthoquinone antiprotozoal drug related to parvaquone and atovaquone; it is a promising compound for the therapy and prophylaxis of all forms of theileriosis.

  • Chemical Name: INK1117
    CAS No.: 1268454-23-4 Purity: Appearances: White to gray Solid
    Brand: Synonyms: Serabelisib;INK1117 Quality Control & MSDS Files:
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    Brief introduction:

    MLN1117 is a selective <b>p110α</b> inhibitor with an <b>IC<sub>50</sub></b> of 15 nM.

  • Chemical Name: 3,3',5-Triiodo-L-thyronine (sodium salt)
    CAS No.: 55-06-1 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: T3 Sodium salt;Sodium L-3,3... Quality Control & MSDS Files:
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    Brief introduction:

    3,3',5-Triiodo-L-thyronine sodium is an active form of thyroid hormone, which binds to <b>β1 thyroid hormone receptor</b> (<b>TRβ1</b>), and activates its activity.

  • Chemical Name: Afobazole (hydrochloride)
    CAS No.: 173352-39-1 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: CM346 hydrochloride Quality Control & MSDS Files:
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  • Chemical Name: Rostafuroxin
    CAS No.: 156722-18-8 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: PST-2238;PST 2238;PST2238; ... Quality Control & MSDS Files:
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    Na+/K+ ATPase modulator. Inhibits the Normalizes renal Na+/K+ ATPase pump function in mutant adducin- and endogenous ouabain-dependent forms of hypertension. Reduces blood pressure in Milan hypertensive rats. Controls mania-like behaviors in Myshkin mice having a Na+/K+ ATPase α3 subunit mutation. Antagonizes the effects of Ouabain (Ca...

  • Chemical Name: Fidaxomycin
    CAS No.: 873857-62-6 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: OPT-80;PAR-101;Dificid;Difi... Quality Control & MSDS Files:
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    Brief introduction:

    Fidaxomicin(OPT-80; PAR-101) is a new class of narrow spectrum macrocyclic antibiotic drug; selective eradication of pathogenic Clostridium difficile with minimal disruption to the multiple species of bacteria that make up the normal, healthy intestinal flora.

  • Chemical Name: GNE-9605
    CAS No.: 1536200-31-3 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: GNE 9605;GNE9605;N2-(5-chlo... Quality Control & MSDS Files:
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    Brief introduction:

    GNE-9605 is a highly potent and selective <b>leucine-rich repeat kinase 2 (LRRK2)</b> inhibitor with <b>K<sub>i</sub></b> and <b>IC50</b> of 2 nM and 19 nM, respectively.

  • Chemical Name: Doxylamine (succinate)
    CAS No.: 562-10-7 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: N,N-Dimethyl-2-[1-phenyl-1-... Quality Control & MSDS Files:
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    Brief introduction:

    Doxylamine is a first generation antihistamine; can be used by itself as a short-term sedative and in combination with other drugs to provide night-time allergy and cold relief.

  • Chemical Name: K02288
    CAS No.: 1431985-92-0 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: K-02288; K 02288; K 02288. Quality Control & MSDS Files:
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    Brief introduction:

    K02288 is a potent inhibitor of <b>ALK</b>, and inhibits ALK1/2/3/6 with <b>IC<sub>50</sub></b>s of 1.8/1.1/34.4/6.3 nM; less potent against ALK4/5, with IC<sub>50</sub>s of 302 nM and 321 nM.

  • Chemical Name: AZ191
    CAS No.: 1594092-37-1 Purity: Appearances: light yellow to khaki Solid
    Brand: Synonyms: AZ 191; N-(2-methoxy-4-(4-m... Quality Control & MSDS Files:
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    Brief introduction:

    AZ191 is a potent and selective <b>DYRK1B</b> inhibitor with <b>IC50</b> of 17 nM in a cell-free assay, about 5- and 110-fold selectivity over DYRK1A and DYRK2, respectively.

  • Chemical Name: MI 2
    CAS No.: 1047953-91-2 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: MALT1 inhibitor Quality Control & MSDS Files:
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    Brief introduction:

    MI 2 (MALT1 inhibitor) is an irreversible <b>MALT1</b> protease inhibitor with an <b>IC<sub>50</sub></b> of 5.84 μM.

  • Chemical Name: CID16020046
    CAS No.: 834903-43-4 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: CID16020046;CID-16020046; 4... Quality Control & MSDS Files:
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    Brief introduction:

    CID 16020046 is a potent and selective GPR55(LPI receptor) antagonist; inhibitsGPR55 constitutive activity with IC50 of 0.15 uM. IC50 value: 0.15 uM [1] Target: GPR55 antagonist In yeast cells expressing human GPR55, CID16020046 antagonized agonist-induced receptor activation.

  • Chemical Name: MIM1
    CAS No.: 509102-00-5 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: MIM 1;MIM-1;Inhibitor of Mc... Quality Control & MSDS Files:
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    Brief introduction:

    MIM1 is a selective small molecule inhibitor of Mcl-1(IC50= 4.8 uM) that overcomes Mcl-1-dependent leukemia cell survival. IC50 value: 4.8 uM Target: Mcl-1 MIM1 effectively competed with FITC-MCL-1 SAHBA and FITC-BID BH3 for MCL-1ΔNΔC binding with respective IC50s of 4.7 and 4.8 μM, the compound showed no capacity to displace FITC-B...