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Apexbio Technology LLC

6991

Basic Information

Company Name:Apexbio Technology LLC

Business Type:Chemical manufacturer since 2012

Total NO.Employees:

Country/Region:USA

Certificates:

Year Established:

Introduction of Apexbio Technology LLC

ApexBio is a premier provider of peptides and lab reagents for biological research. We carry a broad product line in research areas such as Apoptosis, Epigenetics, Cancer Biology and so on. Apexbio also provides custom services including peptide synthesis, antibody production and assay development.

Web: www.apexbt.com TEL:+1-832-696-8203 Fax:+1-832-641-3177 Email:[email protected]

Products of Apexbio Technology LLC

  • Chemical Name: PEAQX
    CAS No.: 459836-30-7 Purity: Appearances:
    Brand: Synonyms: NVP-AAM077 Quality Control & MSDS Files:
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    Brief introduction:

    NVP-AAM077 inhibited progenitor cells proliferation in the subventricular zone and dentate gyrus and reduced the survival of newborn cells in the dentate gyrus in the adult mice.

  • Chemical Name: LY2857785
    CAS No.: 1619903-54-6 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: LY 2857785;LY-2857785; (1r,... Quality Control & MSDS Files:
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    Brief introduction:

    LY2857785 is a type I reversible and competitive ATP kinase inhibitor against <b>CDK9</b> (<b>IC<sub>50</sub></b> 11 nM) and other transcription kinases <b>CDK8</b> (<b>IC<sub>50</sub></b> 16 nM), and <b>CDK7</b> (<b>IC<sub>50</sub></b> 246 nM).

  • Chemical Name: (R)-(+)-Etomoxir sodium salt
    CAS No.: 828934-41-4 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: (+)-Etomoxir sodium salt; s... Quality Control & MSDS Files:
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    Brief introduction:

    (R)-(+)-Etomoxir (sodium salt) is a potent inhibitor of carnitine palmitoyltransferase I (CPT1); inhibits β-oxidation in mitochondria; shown to inhibit cardiolipin biosynthesis from exogenous fatty acid in H9c2 cells.

  • Chemical Name: IM-12
    CAS No.: 1129669-05-1 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: IM 12;IM12; 3-((4-fluorophe... Quality Control & MSDS Files:
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    Brief introduction:

    IM-12 is an inhibitor of <b>GSK-3β</b>, with an <b>IC<sub>50</sub></b> of 53 nM, and also enhances Wnt signalling.

  • Chemical Name: Nexturastat A
    CAS No.: 1403783-31-2 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: 4-((1-butyl-3-phenylureido)... Quality Control & MSDS Files:
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    Description

  • Chemical Name: kb-NB77-78
    CAS No.: 1350622-33-1 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: 9-((tert-butyldimethylsilyl... Quality Control & MSDS Files:
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    Brief introduction:

    kb-NB77-78 is an analog of CID797718, which is a by-product of the synthesis of the parental compound, CID755673(PKD1 inhibitor).

  • Chemical Name: MMAD (hydrochloride)
    CAS No.: 173441-26-4 Purity: Appearances: White to off-white solid
    Brand: Synonyms: Demethyldolastatin 10 hydro... Quality Control & MSDS Files:
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    Brief introduction:

    A potent tubulin inhibitor that is a toxin payload in antibody drug conjugates (ADCs).

  • Chemical Name: HG6-64-1
    CAS No.: 1315329-43-1 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: HG-6-64-1;HG 6-64-1; (E)-N-... Quality Control & MSDS Files:
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    Brief introduction:

    HG6-64-1 is a potent and selective <b>B-Raf</b> inhibitor extracted from patent WO 2011090738 A2, example 9 (XI-1); has a <b>IC<sub>50</sub></b> of 0.09 μM on B-raf V600E transformed Ba/F3 cells.

  • Chemical Name: Dictamnine
    CAS No.: 484-29-7 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: 4-Methoxyfuro[2,3-b]quinoli... Quality Control & MSDS Files:
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    Brief introduction:

    Dictamnine (Dictamine) has the ability to exert cytotoxicity in human cervix, colon, and oral carcinoma cells; A natural plant product has been reported to have antimicrobial activity against bacteria and fungi. IC50 value: Target: Dictamnine has antimicrobial activities against the model fungus Saccharomyces cerevisiae, with a min...

  • Chemical Name: RGDS peptide
    CAS No.: 91037-65-9 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: RGDS peptide;Fibronectin In... Quality Control & MSDS Files:
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    Arg-Gly-Asp-Ser(RGDS peptide) is an integrin binding sequence that inhibits integrin receptor function; decreases systemic inflammation via inhibition of collagen-triggered activation of leukocytes and attenuates expression of inflammatory cytokines, iNOS and MMP-9.

  • Chemical Name: Defactinib
    CAS No.: 1073154-85-4 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: VS-6063;VS6063;VS 6063; N-m... Quality Control & MSDS Files:
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    Brief introduction:

    Defactinib is a novel <b>FAK</b> inhibitor, which inhibits FAK phosphorylation at the Tyr397 site in a time- and dose-dependent manner.

  • Chemical Name: Ozanimod (RPC1063)
    CAS No.: 1306760-87-1 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: RPC-1063 Quality Control & MSDS Files:
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    Brief introduction:

    Ozanimod is a potent and selective <b>S1P<sub>1</sub></b> and <b>S1P<sub>5</sub> receptor</b> agonist with <b>EC<sub>50</sub></b>s of 410±160 pM and 11±4.3 nM in [<sup>35</sup>S]-GTPγS binding, respectively.

  • Chemical Name: YH239-EE
    CAS No.: 1364488-67-4 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: YH 239-EE;YH 239 EE; ethyl ... Quality Control & MSDS Files:
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    Description

  • Chemical Name: PI-1840
    CAS No.: 1401223-22-0 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: PI 1840;PI1840; N-isopropyl... Quality Control & MSDS Files:
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    Description

  • Chemical Name: INK1117
    CAS No.: 1268454-23-4 Purity: Appearances: White to gray Solid
    Brand: Synonyms: Serabelisib;INK1117 Quality Control & MSDS Files:
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    Brief introduction:

    MLN1117 is a selective <b>p110α</b> inhibitor with an <b>IC<sub>50</sub></b> of 15 nM.

  • Chemical Name: NVP-QAV680
    CAS No.: 872365-16-7 Purity: Appearances:
    Brand: Synonyms: NVP-QAV-680 Quality Control & MSDS Files:
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    Brief introduction:

    NVP-QAV-680 is a potent and selective CRTh2 receptor antagonist suitable for clinical testing in allergic diseases. A highly selective compound, it has low nM functional potency for inhibition of CRTh2 driven human eosinophil and Th2 lymphocyte activation in vitro.

  • Chemical Name: Rostafuroxin (PST 2238)
    CAS No.: 156722-18-8 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: PST-2238;PST 2238;PST2238; ... Quality Control & MSDS Files:
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    Brief introduction:

    Na+/K+ ATPase modulator. Inhibits the Normalizes renal Na+/K+ ATPase pump function in mutant adducin- and endogenous ouabain-dependent forms of hypertension. Reduces blood pressure in Milan hypertensive rats. Controls mania-like behaviors in Myshkin mice having a Na+/K+ ATPase α3 subunit mutation. Antagonizes the effects of Ouabain (Ca...

  • Chemical Name: GNE-9605
    CAS No.: 1536200-31-3 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: GNE 9605;GNE9605;N2-(5-chlo... Quality Control & MSDS Files:
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    Brief introduction:

    GNE-9605 is a highly potent and selective <b>leucine-rich repeat kinase 2 (LRRK2)</b> inhibitor with <b>K<sub>i</sub></b> and <b>IC50</b> of 2 nM and 19 nM, respectively.

  • Chemical Name: CDK7-IN-1
    CAS No.: 1604810-84-5 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: THZ2; THZ 2; THZ-2. Quality Control & MSDS Files:
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    Brief introduction:

    THZ2 is a potent and selective <b>CDK7</b> inhibitor with <b>IC<sub>50</sub></b> of 13.9 nM.

  • Chemical Name: THZ2
    CAS No.: 1604810-84-5 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: THZ2; THZ 2; THZ-2. Quality Control & MSDS Files:
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    Brief introduction:

    THZ2 is a potent and selective <b>CDK7</b> inhibitor with <b>IC<sub>50</sub></b> of 13.9 nM.