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Apexbio Technology LLC

1072

Basic Information

Company Name:Apexbio Technology LLC

Business Type:Chemical manufacturer since 2012

Total NO.Employees:

Country/Region:USA

Certificates:

Year Established:

Introduction of Apexbio Technology LLC

ApexBio is a premier provider of peptides and lab reagents for biological research. We carry a broad product line in research areas such as Apoptosis, Epigenetics, Cancer Biology and so on. Apexbio also provides custom services including peptide synthesis, antibody production and assay development.

Web: www.apexbt.com TEL:+1-832-696-8203 Fax:+1-832-641-3177 Email:[email protected]

Products of Apexbio Technology LLC

  • Chemical Name: PEAQX
    CAS No.: 459836-30-7 Purity: Appearances:
    Brand: Synonyms: NVP-AAM077 Quality Control & MSDS Files:
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  • Chemical Name: LY2857785
    CAS No.: 1619903-54-6 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: LY 2857785;LY-2857785; (1r,... Quality Control & MSDS Files:
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    LY2857785 is a type I reversible and competitive ATP kinase inhibitor against <b>CDK9</b> (<b>IC<sub>50</sub></b> 11 nM) and other transcription kinases <b>CDK8</b> (<b>IC<sub>50</sub></b> 16 nM), and <b>CDK7</b> (<b>IC<sub>50</sub></b> 246 nM).

  • Chemical Name: IM-12
    CAS No.: 1129669-05-1 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: IM 12;IM12; 3-((4-fluorophe... Quality Control & MSDS Files:
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    IM-12 is an inhibitor of <b>GSK-3β</b>, with an <b>IC<sub>50</sub></b> of 53 nM, and also enhances Wnt signalling.

  • Chemical Name: Nexturastat A
    CAS No.: 1403783-31-2 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: 4-((1-butyl-3-phenylureido)... Quality Control & MSDS Files:
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    Nexturastat A is a potent and selective HDAC6 inhibitor with IC50 of 5 nM; no inhibition on other HDAC forms. IC50 value: 5 nM [1] Target: HDAC6 inhibitor Nexturastat A displayed low micromolar activity compared to the low nanomolar activity against HDAC6.

  • Chemical Name: kb-NB77-78
    CAS No.: 1350622-33-1 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: 9-((tert-butyldimethylsilyl... Quality Control & MSDS Files:
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    kb-NB77-78 is an analog of CID797718, which is a by-product of the synthesis of the parental compound, CID755673(PKD1 inhibitor).

  • Chemical Name: MMAD (hydrochloride)
    CAS No.: 173441-26-4 Purity: Appearances: White to off-white solid
    Brand: Synonyms: Demethyldolastatin 10 hydro... Quality Control & MSDS Files:
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  • Chemical Name: HG6-64-1
    CAS No.: 1315329-43-1 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: HG-6-64-1;HG 6-64-1; (E)-N-... Quality Control & MSDS Files:
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    HG6-64-1 is a potent and selective <b>B-Raf</b> inhibitor extracted from patent WO 2011090738 A2, example 9 (XI-1); has a <b>IC<sub>50</sub></b> of 0.09 μM on B-raf V600E transformed Ba/F3 cells.

  • Chemical Name: Defactinib
    CAS No.: 1073154-85-4 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: VS-6063;VS6063;VS 6063; N-m... Quality Control & MSDS Files:
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    Defactinib is a novel <b>FAK</b> inhibitor, which inhibits FAK phosphorylation at the Tyr397 site in a time- and dose-dependent manner.

  • Chemical Name: PI-1840
    CAS No.: 1401223-22-0 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: PI 1840;PI1840; N-isopropyl... Quality Control & MSDS Files:
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  • Chemical Name: NVP-QAV680
    CAS No.: 872365-16-7 Purity: Appearances:
    Brand: Synonyms: NVP-QAV-680 Quality Control & MSDS Files:
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  • Chemical Name: BAMB-4
    CAS No.: 891025-25-5 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: ITPKA-IN-C14; N-(benzo[d]is... Quality Control & MSDS Files:
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    BAMB-4(ITPKA-IN-C14) is a new membrane-permeable inhibitor against inositol-1,4,5-trisphosphate-3-kinase A((ITPKA) with IC50 of 37 uM in ADP-Glo Assay. IC50 value: 37 uM Target: ITPKA inhibitor BAMB-4 exhibit the lowest inhibition frequency among the InsP3- Kinase inhibitors.

  • Chemical Name: LDN-27219
    CAS No.: 312946-37-5 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: LDN 27219;LDN 27219; 2-((4-... Quality Control & MSDS Files:
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    LDN-27219 is a potent inhibitor of hTGase(Tissue transglutaminase) with an IC50 of 0.6 uM. IC50 value: 0.6 uM [1] Target: hTGase inhibitor LDN-27219 is a potent inhibitor of the enzyme(hTGase), producing 100% inhibition at the screening concentration of 10 uM.

  • Chemical Name: VU 0240551
    CAS No.: 893990-34-6 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: VU0240551;VU-0240551; N-(4-... Quality Control & MSDS Files:
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    VU 0240551 is a small molecule inhibitor of the neuronal K-Cl cotransporter, KCC2 (IC50 = 560 nM for K+ uptake assay in KCC2-overexpressing cells). IC50 value: 560 nM [1] Target: K-Cl cotransporter(KCC2) VU 0240551 exhibits selectivity over the Na-K-2Cl cotransporter, NKCCl.

  • Chemical Name: FR 180204
    CAS No.: 865362-74-9 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: FR 180204;FR-180204; 5-(2-p... Quality Control & MSDS Files:
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    FR180204 is a potent and selective ATP-competitive inhibitor of ERK1 and ERK2 with Ki value of 0.31 uM and 0.14 uM respectively; has IC50 values of 0.51 and 0.33 μM in enzymatic assays against ERK1 and ERK2, respectively. IC50 value: 0.31 uM/0.14 uM(Ki for ERK1/ERK2); 0.51uM/0.33 μM(ERK1/ERK2) [1] [2] Target: ERK1/2 inhibitor in vi...

  • Chemical Name: ML347
    CAS No.: 1062368-49-3 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: ML 347;ML-347;LDN-193719;LD... Quality Control & MSDS Files:
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    ML347(DN193719) is a highly selective ALK1/ALK2 inhibitor with IC50s of 46/32 nM; shows >300-fold selectivity for ALK2 vs.

  • Chemical Name: CZC-25146
    CAS No.: 1191911-26-8 Purity: Appearances: pale purple to purple Solid
    Brand: Synonyms: CZC25146;CZC 25146; N-(2-((... Quality Control & MSDS Files:
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    CZC-25146 is a potent, selective and metabolically stable LRRK2 inhibitor with IC50 of 4.76 nM/6.87 nM for wild type LRRK2 and G2019S LRRK2 respectively. IC50 value: 4.76 nM/6.87 nM(wild type/G2019S LRRK2) [1] Target: LRRK2 CZC-25146displayed a very clean profile, it inhibited only five kinases(PLK4, GAK, TNK1, CAMKK2 and PIP4K2C) ...

  • Chemical Name: AGN 195183
    CAS No.: 191469-29-1 Purity: Appearances:
    Brand: Synonyms: AGN195183;AGN-195183; 2,6-d... Quality Control & MSDS Files:
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    AGN 195183 is a potent and selective agonist of RARα(Kd=3 nM) with improved binding selectivity relative to AGN 193836; no activity on RARβ/γ. IC50 value: 3 nM (Kd); 200 nM (EC80, RAR Trans.) Target: RARα agonist Compound 4(AGN-195183) inhibited the growth of breast cancer cell lines, and was inactive in an in vivo model of topical ...

  • Chemical Name: AGN 205728
    CAS No.: 859498-05-8 Purity: Appearances: light yellow to khaki Solid
    Brand: Synonyms: AGN205728;AGN-205728; 4-((1... Quality Control & MSDS Files:
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    AGN 205728 is a potent and selective RARγ antagonist with Ki/IC95 values of 3 nM/ 0.6 nM; no inhibiton on RARα and RARβ. IC50 value: 3 nM/ 0.6 nM(Ki/IC95) Target: RARγ antagonist More information can be found in the following patent, Compound 7a. Preparation of disubstituted chalcone oximes having RARγ retinoid receptor antagonist ...

  • Chemical Name: AGN 196996
    CAS No.: 958295-17-5 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: AGN196996;AGN-196996; 4-(3-... Quality Control & MSDS Files:
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    AGN 196996 is a potent and selective RARα antagonist with Ki value of 2 nM; little binding affinity for RARβ(Ki=1087 nM) and RARγ(Ki=8523 nM). IC50 value: 2 nM(Ki) Target: RARα antagonist AGN 196996 shows no activity in transactivation assays, but instead block the gene transcriptional activity induced by ATRA and other RAR agonists.

  • Chemical Name: Helioxanthin 8-1
    CAS No.: 840529-13-7 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: Helioxanthin analogue 8-1; ... Quality Control & MSDS Files:
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    Brief introduction:

    Helioxanthin 8-1 is an analogue of helioxanthin, exhibites significant in vitro anti-HBV/HCV/HSV-1/HIV activity with EC50 of >5/10/1.4/15 uM. IC50 value: >5/10/1.4/15 uM(HBV/HCV/HSV-1/HIV) [1] Target: Antiviral agent The cyclic hydrazide 28(Helioxanthin 8-1) showed the most potent antiHBV activity among those helioxanthin analogues...