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AdooQ BioScience, LLC

4521

Basic Information

Company Name:AdooQ BioScience, LLC

Business Type:Chemical manufacturer since 2006

Total NO.Employees:

Country/Region:USA

Certificates:

Year Established: 2006

Introduction of AdooQ BioScience, LLC

AdooQ BioScience is a supplier of biochemicals located in irvine, CA since 2006. In past five years, we have been a renowned name engaged in manufacturing and supplying small molecule inhibitors including kinase inhibitors on kinds of signal pathway, such as PI3K, AKT, HDAC, MARP etc.

Web: www.adooq.com TEL:855-GO-ADOOQ (855-462-3667) (US & Canada Toll Free) 866-930-6790 (US & Canada Toll Free) +1-323-389-9269 (Outside of US & Canada) Fax:866-333-9607 (US & Canada Toll Free) +1-323-606-8156 (Outside of US & Canada) Email:[email protected]

Products of AdooQ BioScience, LLC

  • Chemical Name: AMG 837
    CAS No.: 1259389-38-2 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: AMG-837 calcium hydrate;AMG... Quality Control & MSDS Files:
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    Brief introduction:

    AMG-837 is a potent, orally bioavailable GPR40 agonist.

  • Chemical Name: AMG 837 (sodium salt)
    CAS No.: 865231-45-4 Purity: Appearances:
    Brand: Synonyms: AMG-837 sodium salt;AMG837 ... Quality Control & MSDS Files:
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    Brief introduction:

    AMG 837 sodium salt is a potent GPR40 agonist(EC50=13 nM) with a superior pharmacokinetic profile and robust glucose-dependent stimulation of insulin secretion in rodents. IC50 value: 13 nM (EC50) [1] Target: GPR40 agonist AMG 837 displayed the expected two-fold increase in potency on GPR4 (EC50 = 13 [±7] nM) compared to the racemic...

  • Chemical Name: NVP-AAM077 Tetrasodium Hydrate (PEAQX)
    CAS No.: 459836-30-7 Purity: Appearances:
    Brand: Synonyms: NVP-AAM077 Quality Control & MSDS Files:
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    Brief introduction:

    NVP-AAM077 inhibited progenitor cells proliferation in the subventricular zone and dentate gyrus and reduced the survival of newborn cells in the dentate gyrus in the adult mice.

  • Chemical Name: LY2857785
    CAS No.: 1619903-54-6 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: LY 2857785;LY-2857785; (1r,... Quality Control & MSDS Files:
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    Brief introduction:

    LY2857785 is a potent and selective CDK9 inhibitor; significantly reduces RNAP II CTD phosphorylation and dramatically decreases MCL1 protein levels to result in apoptosis in a variety of leukemia and solid tumor cell lines.

  • Chemical Name: Etomoxir (sodium salt)
    CAS No.: 828934-41-4 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: (+)-Etomoxir sodium salt; s... Quality Control & MSDS Files:
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    Brief introduction:

    Etomoxir is an inhibitor of carnitine palmitoyltransferase A (CPT1), which is required for the oxidation of long-chain acyl CoA esters. Also a strong inhibitor of mitochondrial CPT1 and a candidate as an anti-diabetic drug.

  • Chemical Name: IM-12
    CAS No.: 1129669-05-1 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: IM 12;IM12; 3-((4-fluorophe... Quality Control & MSDS Files:
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    Brief introduction:

    IM-12 is a cell-permeable indolylmaleimide that acts as a Glycogen synthase kinase 3β (GSK-3β) inhibitor, activating downstream components of canonical Wnt signaling.

  • Chemical Name: Nexturastat A
    CAS No.: 1403783-31-2 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: 4-((1-butyl-3-phenylureido)... Quality Control & MSDS Files:
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    Brief introduction:

    Nexturastat A is an aryl urea derivative that acts as a potent and highly selective inhibitor of histone deacetylase 6 (HDAC6) (IC50= 5.02 +/- 0.60 nM).

  • Chemical Name: HG6-64-1
    CAS No.: 1315329-43-1 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: HG-6-64-1;HG 6-64-1; (E)-N-... Quality Control & MSDS Files:
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    Brief introduction:

    HG6-64-1 is a potent and selective B-Raf and mutant B-Raf inhibitor; more information can be found in Patent WO 2011090738.

  • Chemical Name: 4SC-202
    CAS No.: 910462-43-0 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: 4SC 202 free base;4SC202 fr... Quality Control & MSDS Files:
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    Brief introduction:

    4SC-202 is an orally bioavailable benzamide and inhibitor of human class I histone deacetylases (HDACs) isoenzymes 1, 2 and 3, with potential antineoplastic activity.

  • Chemical Name: PF-04554878 (Defactinib)
    CAS No.: 1345713-71-4, 1073154-85-4 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: VS-6063;VS6063;VS 6063; N-m... Quality Control & MSDS Files:
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    Brief introduction:

    PF-04554878 is a novel FAK kinase inhibitor that decreases growth and induces apoptosis in pancreatic neuroendocrine tumor cells

  • Chemical Name: RPC1063 (Ozanimod)
    CAS No.: 1306760-87-1 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: RPC-1063 Quality Control & MSDS Files:
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    Brief introduction:

    RPC1063 is a selective sphingosine 1 phosphate receptor modulators and methods which may be useful in the treatment of S1P1-?associated diseases.

  • Chemical Name: YH239-EE
    CAS No.: 1364488-67-4 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: YH 239-EE;YH 239 EE; ethyl ... Quality Control & MSDS Files:
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    Brief introduction:

    YH239-EE is a potent p53-MDM2 antagonist and an apoptosis inducer.

  • Chemical Name: PI-1840
    CAS No.: 1401223-22-0 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: PI 1840;PI1840; N-isopropyl... Quality Control & MSDS Files:
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    Brief introduction:

    PI-1840 is a novel noncovalent and rapidly reversible proteasome inhibitor with anti-tumor activity.

  • Chemical Name: MLN1117 (Serabelisib)
    CAS No.: 1268454-23-4 Purity: Appearances: White to gray Solid
    Brand: Synonyms: Serabelisib;INK1117 Quality Control & MSDS Files:
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    Brief introduction:

    MLN1117, also known as INK1117 and TAK-117, is an orally bioavailable inhibitor of the class I phosphoinositide 3-kinase (PI3K) alpha isoform with potential antineoplastic activity.

  • Chemical Name: Rostafuroxin (PST-2238)
    CAS No.: 156722-18-8 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: PST-2238;PST 2238;PST2238; ... Quality Control & MSDS Files:
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    Brief introduction:

    Rostafuroxin (PST-2238) is an ouabain-inhibitor counteracting specific forms of hypertension.

  • Chemical Name: Fidaxomicin
    CAS No.: 873857-62-6 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: OPT-80;PAR-101;Dificid;Difi... Quality Control & MSDS Files:
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    Brief introduction:

    Fidaxomicin is the major analogue of a family of macrocyclic lactones isolated independently by three different groups from cultures belonging to three different genera (Actinoplanes, Dactylosporangium and Micromonospora) known as lipiarmycin A3, tiacumicin B and clostomicin B1, respectively. Fidaxomicin is a narrow spectrum antibioti...

  • Chemical Name: Micafungin
    CAS No.: 235114-32-6 Purity: Appearances:
    Brand: Synonyms: Mycamine;FK463;Funguard; 5-... Quality Control & MSDS Files:
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    Brief introduction:

    Micafungin (Mycamine; FK463) is an echinocandin antifungal drug which can inhibit 1,3-beta-D-glucan synthase.

  • Chemical Name: GNE 9605
    CAS No.: 1536200-31-3 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: GNE 9605;GNE9605;N2-(5-chlo... Quality Control & MSDS Files:
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    Brief introduction:

    GNE-9605 is a highly potent and selective leucine-rich repeat kinase 2 (LRRK2) inhibitor with Ki and IC50 of 2 nM and 19 nM, respectively.

  • Chemical Name: FPH2 (BRD-9424)
    CAS No.: 957485-64-2 Purity: Appearances:
    Brand: Synonyms: FPH 2;FPH-2;BRD-9424;BRD 94... Quality Control & MSDS Files:
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    Brief introduction:

    FPH2 (BRD-9424) is a small molecule, which promotes differentiation of iPS-derived hepatocytes.

  • Chemical Name: Pirarubicin (Hydrochloride)
    CAS No.: 95343-20-7 Purity: Appearances: Pink to red Solid
    Brand: Synonyms: THP Hydrochloride; (8S,10S)... Quality Control & MSDS Files:
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    Brief introduction:

    Pirarubicin Hcl is an analogue of the anthracycline anti-neoplastic doxorubicin, which is an inhibitor of Topo II. Target: Topoisomerase Pirarubicin is an anthracycline drug.