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Vadadustat

(CAS: 1000025-07-9)

Suppliers of Vadadustat

Company Name Email Tel Country
Ark Pharm, Inc. [email protected] +1 (847) 367-3680 USA

Fax: +1 (847) 367-3681Purity: Brand:

BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: >98 % Brand: BOC Sciences

Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

Fax: Purity: 98% Brand: Biochempartner

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD70/2mg () USD120/5mg ()

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD70/2mg () USD120/5mg ()
Quality Control & MSDS Files: LCMS HNMR MSDS

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

Fax: 919-980-4831Purity: Brand:

ProbeChem [email protected] 86-21-80183644

Fax: 86-21-68860190Purity: Brand:

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD70/2mg () USD120/5mg ()

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Background Information of Vadadustat

Vadadustat is a novel, titratable, oral hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor in development for the treatment of anemia.

Solubility of Vadadustat

Solubility Sources
DMSO: ≥ 33 mg/mL CHEMSCENE, LLC
DMSO: ≥ 33 mg/mL MedChemexpress Co., Ltd.

Storage Condition of Vadadustat

Storage Condition Sources

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[LCMS] [HNMR] MedChemexpress Co., Ltd.

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Vadadustat Akebia Therapeutics Healthy Volunteers 2014/12/01 Phase 1
Vadadustat Akebia Therapeutics Anemia|Kidney Disease 2010/10/01 Phase 2
Vadadustat Akebia Therapeutics Healthy Volunteers 2015/7/01 Phase 1
Vadadustat Akebia Therapeutics Healthy Volunteers 2014/1/01 Phase 1
Vadadustat Akebia Therapeutics Anemia|Kidney Disease 2011/6/01 Phase 2
Vadadustat Akebia Therapeutics Healthy 2015/4/01 Phase 1
Vadadustat Akebia Therapeutics Anemia|Chronic Kidney Disease 2013/7/01 Phase 2
Vadadustat Akebia Therapeutics Anemia|End Stage Renal Disease 2014/9/01 Phase 2
Vadadustat Akebia Therapeutics Anemia|Dialysis-Dependent Chronic Kidney Disease 2017/5/23 Phase 2
Vadadustat Akebia Therapeutics Anemia; Dialysis Dependent Chronic Kidney Disease 2016/12/01 Phase 2
Vadadustat Akebia Therapeutics Anemia; Non-dialysis Dependent Chronic Kidney Disease 2016/10/01 Phase 2
Vadadustat Akebia Therapeutics Anemia|Non-dialysis-dependent Chronic Kidney Disease 2015/12/01 Phase 3
Vadadustat Akebia Therapeutics Anemia|Dialysis-dependent Chronic Kidney Disease 2016/7/01 Phase 3
Vadadustat Akebia Therapeutics Anemia|Non-dialysis-dependent Chronic Kidney Disease 2016/2/01 Phase 3
Vadadustat Akebia Therapeutics Anemia in Subjects With DD-CKD 2016/8/01 Phase 3

Chemical Information

M.Wt Formula CAS No. Synonyms
0.0 C14H11ClN2O4 1000025-07-9 PG-1016548;PG1016548;PG 1016548; 2-(5-(3-chlorophenyl)-3-hydroxypicolinamido)acetic acid

Structure Information of Vadadustat

Smiles O=C(O)CNC(C1=NC=C(C2=CC=CC(Cl)=C2)C=C1O)=O
InChI InChI=1S/C14H11ClN2O4/c15-10-3-1-2-8(4-10)9-5-11(18)13(16-6-9)14(21)17-7-12(19)20/h1-6,18H,7H2,(H,17,21)(H,19,20)

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Chemical and Physical Properties

Appearance: Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:DMSO: ≥ 33 mg/mL
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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