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Seletalisib

(CAS: 1362850-20-1)

Suppliers of Seletalisib

Company Name Email Tel Country
BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: 98% Brand: BOC Sciences

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD132/1mg () USD396/5mg ()

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD132/1mg () USD396/5mg ()
Quality Control & MSDS Files: HNMR LCMS MSDS

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

Fax: 919-980-4831Purity: Brand:

ProbeChem [email protected] 86-21-80183644

Fax: 86-21-68860190Purity: Brand:

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD132/1mg () USD396/5mg ()

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Background Information of Seletalisib

immunomodulator, phosphatidylinositol 3-kinase inhibitor

Solubility of Seletalisib

Solubility Sources
DMSO: ≥83.3 mg/mL CHEMSCENE, LLC
DMSO: ≥83.3 mg/mL MedChemexpress Co., Ltd.

Storage Condition of Seletalisib

Storage Condition Sources

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [LCMS] MedChemexpress Co., Ltd.

Mechanism and Indications

Signaling Pathways PI3K/Akt/mTOR
Target PI3K
Research Area Inflammation/Immunology
Indications Psoriasis Healthy Volunteers Primary Sjogren's Syndrome

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Seletalisib UCB Pharma|Parexel Psoriasis 2013/8/01 Phase 1
Seletalisib UCB Celltech|Parexel|UCB Pharma Healthy Volunteers 2014/8/01 Phase 1
Seletalisib UCB Celltech|PRA Health Sciences|UCB Pharma Primary Sjogren's Syndrome 2015/10/01 Phase 2

Chemical Information

M.Wt Formula CAS No. Synonyms
482.85 C23H14ClF3N6O 1362850-20-1 (R)-3-(8-chloro-3-(2,2,2-trifluoro-1-(pyrido[3,2-d]pyrimidin-4-ylamino)ethyl)quinolin-2-yl)pyridine 1-oxide

Structure Information of Seletalisib

Smiles FC(F)(F)[[email protected]@H](C1=CC(C=CC=C2Cl)=C2N=C1C3=CN(=O)=CC=C3)NC4=NC=NC5=C4N=CC=C5
InChI InChI=1S/C23H14ClF3N6O/c24-16-6-1-4-13-10-15(18(31-19(13)16)14-5-3-9-33(34)11-14)21(23(25,26)27)32-22-20-17(29-12-30-22)7-2-8-28-20/h1-12,21H,(H,29,30,32)/t21-/m1/s1

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Chemical and Physical Properties

Appearance: Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:DMSO: ≥83.3 mg/mL
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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