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KX2-391 (dihydrochloride)

(CAS: 1038395-65-1)

Suppliers of KX2-391 (dihydrochloride)

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AdooQ BioScience, LLC [email protected] 855-GO-ADOOQ (855-462-3667) (US & Canada Toll Free) 866-930-6790 (US & Canada Toll Free) +1-323-389-9269 (Outside of US & Canada) USA

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Price and Availability: USD84/5mg () USD144/10mg ()

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

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Price and Availability: USD84/5mg () USD144/10mg ()
Quality Control & MSDS Files: HNMR LCMS LCMS MSDS

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Background Information of KX2-391 (dihydrochloride)

KX2-391 2Hcl (KX01) is the first clinical Src inhibitor (peptidomimetic class) that targets the peptide substrate site of Src, with GI50 of 9-60 nM in cancer cell lines.

Solubility of KX2-391 (dihydrochloride)

Solubility Sources
DMSO MedChemexpress Co., Ltd.

Storage Condition of KX2-391 (dihydrochloride)

Storage Condition Sources

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [LCMS] MedChemexpress Co., Ltd.

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
KX2-391 (dihydrochloride) Kinex Pharmaceuticals Corp Hormone refractory prostate cancer 2010/2/28 2012/8/31 Phase 2 Clinical
KX2-391 (dihydrochloride) Hanmi Pharmaceutical Co Ltd Advanced solid tumor 2012/12/31 2016/5/31 Phase 2 Clinical
KX2-391 (dihydrochloride) Kinex Pharmaceuticals Corp Acute myelogenous leukemia 2011/7/31 2013/10/31 Phase 1 Clinical
KX2-391 (dihydrochloride) Kinex Pharmaceuticals Corp Lymphoma 2007/11/30 2011/5/31 Phase 1 Clinical
KX2-391 (dihydrochloride) Kinex Pharmaceuticals Corp Solid tumor 2007/11/30 2011/5/31 Phase 1 Clinical
KX2-391 (dihydrochloride) - Phase 2

Chemical Information

M.Wt Formula CAS No. Synonyms
504.45 C26H31Cl2N3O3 1038395-65-1 KX2-391 2HCl; KX2-391; N-benzyl-2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)acetamide dihydrochloride

Structure Information of KX2-391 (dihydrochloride)

Smiles O=C(CC1=NC=C(C2=CC=C(OCCN3CCOCC3)C=C2)C=C1)NCC4=CC=CC=C4.Cl.Cl
InChI InChI=1S/C26H29N3O3.2ClH/c30-26(28-19-21-4-2-1-3-5-21)18-24-9-6-23(20-27-24)22-7-10-25(11-8-22)32-17-14-29-12-15-31-16-13-29;;/h1-11,20H,12-19H2,(H,28,30);2*1H

Related Products

Other Form Products of KX2-391 (dihydrochloride)

Name CAS Formula Suppliers
KX2-391 897016-82-9 C26H29N3O3 14
KX2-391 (Mesylate) 1080645-95-9 C27H33N3O6S 5

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Recommended Products in the Same Indication

Name CAS Formula Suppliers
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PU-H71 873436-91-0 C18H21IN6O2S 9
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MGCD-265 analog 875337-44-3 C26H20FN5O2S2 14
Regorafenib (Hydrochloride) 835621-07-3 C21H16Cl2F4N4O3 10
AT9283 896466-04-9 C19H23N7O2 21
KX2-391 897016-82-9 C26H29N3O3 14
Bicalutamide 90357-06-5 C18H14F4N2O4S 30
Bleomycin (sulfate) 9041-93-4 C110H168N34O46S7 24
MLN4924 905579-51-3 C21H25N5O4S 16
SNX-2112 908112-43-6 C23H27F3N4O3 12

Chemical and Physical Properties

Appearance:White to off-white solid Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:>25.2mg/mL in DMSO
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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