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CHF5074

(CAS: 749269-83-8)

Suppliers of CHF5074

Company Name Email Tel Country
AOBIOUS INC [email protected] (508) 306-0937 USA

Fax: Purity: Brand:

Price and Availability: USD53/1mg ()

AdooQ BioScience, LLC [email protected] 855-GO-ADOOQ (855-462-3667) (US & Canada Toll Free) 866-930-6790 (US & Canada Toll Free) +1-323-389-9269 (Outside of US & Canada) USA

Fax: 866-333-9607 (US & Canada Toll Free) +1-323-606-8156 (Outside of US & Canada)Purity: Brand:

Ark Pharm, Inc. [email protected] +1 (847) 367-3680 USA

Fax: +1 (847) 367-3681Purity: Brand:

BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: 98% Brand: BOC Sciences

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD420/5mg () USD600/10mg ()

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD420/5mg () USD600/10mg ()
Quality Control & MSDS Files: HNMR NP-HPLC

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

Fax: 919-980-4831Purity: Brand:

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

Fax: 919-980-4831Purity: Brand:

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD420/5mg () USD600/10mg ()

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .98 Brand: TargetMol

Price and Availability: USD222/2mg () USD346/5mg () USD498/10mg () USD1470/50mg ()

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Background Information of CHF5074

CHF5074 is a novel γ-secretase modulator, reduces Aβ42 and Aβ40 secretion, with an IC50 of 3.6 and 18.4 uM, respectively.

Solubility of CHF5074

Solubility Sources
DMSO:37mg/mL CHEMSCENE, LLC
DMSO:37mg/mL MedChemexpress Co., Ltd.

Storage Condition of CHF5074

Storage Condition Sources
4°C MedChemexpress Co., Ltd.

MSDS Information

MSDS Sources

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [NP-HPLC] MedChemexpress Co., Ltd.

Mechanism and Indications

Signaling Pathways Neuronal Signaling Stem Cell/Wnt
Target γ-secretase
Research Area Neurological Disease
Indications Alzheimer's Disease

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
CHF5074 CERESPIR Alzheimer's Disease 2011/2/23 2015/2/01 Phase 2 Clinical
CHF5074 - Phase 1

Chemical Information

M.Wt Formula CAS No. Synonyms
325.1617 C16H11Cl2FO2 749269-83-8 CSP-1103;Itanapraced

Structure Information of CHF5074

Smiles OC(C1(CC1)C(C=C2)=CC(F)=C2C3=CC=C(Cl)C(Cl)=C3)=O
InChI InChI=1S/C16H11Cl2FO2/c17-12-4-1-9(7-13(12)18)11-3-2-10(8-14(11)19)16(5-6-16)15(20)21/h1-4,7-8H,5-6H2,(H,20,21)

Related Products

Other Form Products of CHF5074

Name CAS Formula Suppliers

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L-685458 292632-98-5 C39H52N4O6 14
Z-Ile-Leu-aldehyde 161710-10-7 C20H30N2O4 9

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THK5351 1707147-26-9 C18H18FN3O2 3
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Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:DMSO
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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