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Brivaracetam

(CAS: 357336-20-0)

Suppliers of Brivaracetam

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Alfa Chemistry [email protected] 1-201-478-8534 USA

Fax: 1-516-927-0118Purity: 0.96 Brand: Alfa Chemistry

Apexbio Technology LLC [email protected] +1-832-696-8203 USA

Fax: +1-832-641-3177Purity: Brand:

Price and Availability: USD95/10mg ()

Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

Fax: Purity: 98% Brand: Biochempartner

Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

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MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

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Pure Chemistry Scientific Inc. [email protected] 857-928-2050 / 857-366-6788 USA

Fax: 617-206-9595Purity: 98% ee99% Brand:

Price and Availability: USD169/1g (In stock)

Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

Fax: +1-832-582-8590Purity: Brand:

Toronto Research Chemicals Inc. [email protected] +1 (416) 665-9696 Canada

Fax: +1 (416) 665-4439Purity: Brand:

Price and Availability: USD65/1mg ()

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Background Information of Brivaracetam

Brivaracetam is a novel high affinity SV2A ligand, which dose-dependently inhibits voltage-dependent sodium currents and reverses the inhibitory effects of negative modulators on γ-aminobutyric acid- and glycine-induced currents.

Solubility of Brivaracetam

Solubility Sources

Storage Condition of Brivaracetam

Storage Condition Sources

MSDS Information

MSDS Sources

Quality Control and Spectral Data

QC Reports Sources

Mechanism and Indications

Signaling Pathways Membrane Transporter/Ion Channel
Target Sodium Channel
Research Area Neurological Disease
Indications Healthy Volunteers Unverricht-Lundborg Disease Epilepsy

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Brivaracetam UCB Pharma Healthy Volunteers 2013/2/19 Phase 1 Clinical
Brivaracetam UCB Pharma Unverricht-Lundborg Disease 2006/8/23 Phase 3 Clinical
Brivaracetam UCB Pharma Epilepsy 2007/6/21 Phase 3 Clinical
Brivaracetam UCB Pharma Epilepsy 2005/9/09 Phase 2 Clinical
Brivaracetam - Launched

Chemical Information

M.Wt Formula CAS No. Synonyms
212.2887 C11H20N2O2 357336-20-0 UCB 34714

Structure Information of Brivaracetam

Smiles CC[[email protected]](N1C(C[[email protected]@H](CCC)C1)=O)C(N)=O
InChI InChI=1S/C11H20N2O2/c1-3-5-8-6-10(14)13(7-8)9(4-2)11(12)15/h8-9H,3-7H2,1-2H3,(H2,12,15)/t8-,9+/m1/s1

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Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:In vitro:DMSO,42 mg/mL(197.84 mM);In vitro:Water,42 mg/mL(197.84 mM);In vitro:Ethanol,42 mg/mL(197.84 mM);
Density:1.062 Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha: yms(alphaS,4R)-alpha-Ethyl-2-oxo-4-propyl-1-pyrrolidineacetamide; UCB-34714

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