• Search chemicals, activators, Inhibitors, APIs, intermediates and raw materials.

Azeliragon

(CAS: 603148-36-3)

Suppliers of Azeliragon

Company Name Email Tel Country
Alfa Chemistry [email protected] 1-201-478-8534 USA

Fax: 1-516-927-0118Purity: 0.96 Brand: Alfa Chemistry

Ark Pharm, Inc. [email protected] +1 (847) 367-3680 USA

Fax: +1 (847) 367-3681Purity: Brand:

BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: ≥98% Brand: BOC Sciences

BioVision, Inc., [email protected] 408-493-1800 Toll Free: 800-891-9699 (US Only) USA

Fax: 408-493-1801Purity: Brand:

Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

Fax: Purity: 98% Brand: Biochempartner

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD144/5mg () USD228/10mg ()

Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

Fax: (734) 971-3640Purity: Brand:

MAYA-R [email protected] 40066-10775 China

Fax: Purity: Brand:

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD144/5mg () USD228/10mg ()
Quality Control & MSDS Files: HNMR LCMS MSDS

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

Fax: 919-980-4831Purity: Brand:

ProbeChem [email protected] 86-21-80183644

Fax: 86-21-68860190Purity: Brand:

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD144/5mg () USD228/10mg ()

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .98 Brand: TargetMol

Price and Availability: USD133/5mg () USD255/10mg () USD694/50mg ()

Inquiry Online

Salutation: *Country:
*Customer: *Company Name:
*Email: *Request quantity:
Remarks:
 

Notice: Your contact information will be sent to selected suppliers.

* Required Fields.

Background Information of Azeliragon

Azeliragon free base, also known as TTP488 and PF-04494700, is a potent and orally active RAGE inhibitor. RAGE (receptor for advanced glycation endproducts) is a pattern recognition receptor, which affects the movement of amyloid, an Alzheimer's-associated protein, into the brain. In preclinical studies, azeliragon decreased brain amyloid in mice and improved their performance on behavior tests. Azeliragon is a promising agent for for Alzheimer's disease and cerebral amyloid angiopathy.

Solubility of Azeliragon

Solubility Sources
10 mM in DMSO CHEMSCENE, LLC
10 mM in DMSO MedChemexpress Co., Ltd.

Storage Condition of Azeliragon

Storage Condition Sources
4°C MedChemexpress Co., Ltd.

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [LCMS] MedChemexpress Co., Ltd.

Mechanism and Indications

Signaling Pathways Others
Target Others
Research Area Neurological Disease
Indications Alzheimer's Disease

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Azeliragon TransTech Pharma, LLC. Alzheimer's Disease 2014/2/25 2015/7/01 Phase 3 Clinical
Azeliragon - Phase 3

Chemical Information

M.Wt Formula CAS No. Synonyms
532.116 C32H38ClN3O2 603148-36-3 TTP488

Structure Information of Azeliragon

Smiles ClC1=CC=C(C=C1)OC2=CC=C(C=C2)N3C(CCCC)=NC(C(C=C4)=CC=C4OCCCN(CC)CC)=C3
InChI InChI=1S/C32H38ClN3O2/c1-4-7-9-32-34-31(25-10-16-28(17-11-25)37-23-8-22-35(5-2)6-3)24-36(32)27-14-20-30(21-15-27)38-29-18-12-26(33)13-19-29/h10-21,24H,4-9,22-23H2,1-3H3

Related Products

Other Form Products of Azeliragon

Name CAS Formula Suppliers

Recommended Products in Same Target

Name CAS Formula Suppliers
(R)-(+)-Etomoxir (sodium salt) 828934-41-4 C15H18ClNaO4 15
Dictamine 484-29-7 C12H9NO2 7
3,3',5-Triiodo-L-thyronine (sodium) 55-06-1 C15H11I3NNaO4 19
Fabomotizole (hydrochloride) 173352-39-1 C15H22ClN3O2S 8
FPH2 957485-64-2 C14H16ClN5O2S 10
α-Tocopherol (phosphate) 38976-17-9 C29H51O5P 6
BAMB-4 891025-25-5 C15H12N2O2 8
LDN-27219 312946-37-5 C20H16N4O2S2 8
ISO-1 478336-92-4 C12H13NO4 16
Aurothioglucose 12192-57-3 C6H11AuO5S 9
Oxybenzone 131-57-7 C14H12O3 38
ITX3 347323-96-0 C22H17N3OS 10
Cardiogreen 3599-32-4 C43H47N2NaO6S2 8
Skp2 Inhibitor C1 432001-69-9 C18H13BrN2O4S2 13
INH1 313553-47-8 C18H16N2OS 12
PF6-AM 1268491-69-5 C33H31BO12 4
XEN445 1515856-92-4 C18H17F3N2O3 21
Disperse Blue 148 52239-04-0 C19H19N5O4S 5
Solvent Blue 35 17354-14-2 C22H26N2O2 6
CID-797718 370586-05-3 C12H11NO3 12

Recommended Products in the Same Indication

Name CAS Formula Suppliers
CHF5074 749269-83-8 C16H11Cl2FO2 10
LY451395 375345-95-2 C21H30N2O4S2 9
MSDC 0160 146062-49-9 C19H18N2O4S 13
THK5351 1707147-26-9 C18H18FN3O2 3
MK-0249 862309-06-6 C23H24F3N3O2 6

Chemical and Physical Properties

Appearance:Light yellow to yellow Solid Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:Soluble in DMSO, not in water
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

Tags: buy Azeliragon | Azeliragon IC50 | Azeliragon price | Azeliragon cost | Azeliragon solubility | Azeliragon purchase | Azeliragon manufacturer | Azeliragon research buy | Azeliragon order | Azeliragon MSDS | Azeliragon chemical structure | Azeliragon Storage condition | Azeliragon molecular weight | Azeliragon mw | Azeliragon datasheet | Azeliragon supplier | Azeliragon cell line | Azeliragon NMR | Azeliragon MS | Azeliragon IR | Azeliragon solubility | Azeliragon Safe information | Azeliragon Qc and Spectral Information | Azeliragon Clinical Information | Azeliragon Clinical Trial | Azeliragon Route of Synthesis | Azeliragon storage condition | Azeliragon diseases and conditions | Azeliragon flash point | Azeliragon boiling point | Azeliragon melting point | Azeliragon storage condition | Azeliragon brand