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Mizolastine

(CAS: 108612-45-9)

Suppliers of Mizolastine

Company Name Email Tel Country
BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: >98% Brand: BOC Sciences

Beijing Dezhong Wanquan Medicines Technological Development Co., Ltd. [email protected] +86 (10) 8850-0088 ex 206 China

Fax: +86 (10) 8850-0080Purity: Brand:

Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

Fax: Purity: 0.98 Brand: Biochempartner

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD125/100mg () USD226/200mg ()

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD125/100mg () USD226/200mg ()
Quality Control & MSDS Files: LCMS HNMR

Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

Fax: +1-832-582-8590Purity: >98% Brand:

Price and Availability: USD97/50mg (In stock)
Quality Control & MSDS Files: HNMR HPLC HNMR HPLC

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD125/100mg () USD226/200mg ()

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .98 Brand: TargetMol

Price and Availability: USD20/2mg () USD68/10mg () USD198/50mg ()

Tianjin Dejia Unite Petrochemical Ltd [email protected] 022 81600347 CHINA

Fax: 022 85721344Purity: Brand:

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Background Information of Mizolastine

Mizolastine is a histamine H1-receptor antagonist with IC50 of 47 nM used in the treatment of hay fever (seasonal allergic rhinitis), hives and other allergic reactions.

Solubility of Mizolastine

Solubility Sources
DMSO <1 mg/mL (<1 mM); Water <1 mg/mL (<1 mM) MedChemexpress Co., Ltd.
(25°C) * In vitro DMSO <1 mg/mL (<1 mM); Water<1 mg/mL (<1 mM); Ethanol<1 mg/mL warming (<1 mM) Selleck Chemicals LLC

Storage Condition of Mizolastine

Storage Condition Sources

MSDS Information

MSDS Sources

Quality Control and Spectral Data

QC Reports Sources
[LCMS] [HNMR] MedChemexpress Co., Ltd.
[HNMR] [HPLC] Selleck Chemicals LLC

Mechanism and Indications

Signaling Pathways Immunology/Inflammation GPCR/G Protein
Target Histamine Receptor
Research Area Inflammation/Immunology
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Mizolastine - Launched

Chemical Information

M.Wt Formula CAS No. Synonyms
432.49 C24H25FN6O 108612-45-9 Mizollen; 2-((1-(1-(4-fluorobenzyl)-1H-benzo[d]imidazol-2-yl)piperidin-4-yl)(methyl)amino)pyrimidin-4(3H)-one

Structure Information of Mizolastine

Smiles O=C1NC(N(C2CCN(C3=NC4=CC=CC=C4N3CC5=CC=C(F)C=C5)CC2)C)=NC=C1
InChI InChI=1S/C24H25FN6O/c1-29(23-26-13-10-22(32)28-23)19-11-14-30(15-12-19)24-27-20-4-2-3-5-21(20)31(24)16-17-6-8-18(25)9-7-17/h2-10,13,19H,11-12,14-16H2,1H3,(H,26,28,32)

Related Products

Other Form Products of Mizolastine

Name CAS Formula Suppliers
Mizolastine (dihydrochloride) 1056596-82-7 C24H27Cl2FN6O 4

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Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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