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Rizatriptan (benzoate)

(CAS: 145202-66-0)

Suppliers of Rizatriptan (benzoate)

Company Name Email Tel Country
Asia Talent Chemical Limited [email protected],[email protected],[email protected] +86 (755) 8665-5561 China

Fax: +86 (755) 8665-5591Purity: Brand:

BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: >98% Brand: BOC Sciences

Beijing Gaobo Pharm-Chemicals Tech. Co., Ltd [email protected] 010-52266256 CHINA

Fax: +86-010-83695064Purity: Brand:

Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

Fax: Purity: 0.98 Brand: Biochempartner

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD50/10mg () USD160/50mg ()

Langfang Gaobo Jingband Pharmaceutical Co., Ltd. [email protected],[email protected] +86 (10) 8369-4934 / +86 13911386546 China

Fax: +86 (10) 8369-5064Purity: Brand:

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD50/10mg () USD160/50mg ()
Quality Control & MSDS Files: HNMR LCMS

Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

Fax: +1-832-582-8590Purity: >98% Brand:

Price and Availability: USD110/10mg (In stock) USD140/10mM/1mLIn DMSO (In stock) USD370/50mg (In stock) USD670/100mg (In stock)

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD50/10mg () USD160/50mg ()

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .98 Brand: TargetMol

Price and Availability: USD36/2mg () USD65/10mg () USD115/25mg ()

Tocris Bioscience Inc. [email protected]; [email protected] +1 (636) 207-7651 USA

Fax: +1 (636) 207-7683Purity: #99 % Brand: Tocris

Yitai Pharmatech Co., Ltd. [email protected] +86 (10) 6780-6114 / +86 13811836936 China

Fax: +86 (10) 6780-6115Purity: Brand:

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Background Information of Rizatriptan (benzoate)

Rizatriptan Benzoate(Maxalt) is a 5-HT1 agonist triptan drug for the treatment of migraine headaches. Target: 5-HT1 agonist Rizatriptan Benzoate(Maxalt) is a 5-HT1 agonist triptan drug for the treatment of migraine headaches.

Solubility of Rizatriptan (benzoate)

Solubility Sources
DMSO 20 mg/mL (51 mM); Water 46 mg/mL (117 mM) MedChemexpress Co., Ltd.
(25°C) * In vitro DMSO 20 mg/mL (51.08 mM); Water46 mg/mL (117.5 mM); Ethanol<1 mg/mL (<1 mM) Selleck Chemicals LLC
Soluble to 100 mM in water and to 50 mM in DMSO Tocris Bioscience Inc.

Storage Condition of Rizatriptan (benzoate)

Storage Condition Sources
Store at RT Tocris Bioscience Inc.

MSDS Information

MSDS Sources

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [LCMS] MedChemexpress Co., Ltd.
[HNMR] [HPLC] Selleck Chemicals LLC

Mechanism and Indications

Signaling Pathways Neuronal Signaling GPCR/G Protein
Target 5-HT Receptor
Research Area Neurological Disease

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Rizatriptan (benzoate) - Launched

Chemical Information

M.Wt Formula CAS No. Synonyms
391.47 C22H25N5O2 145202-66-0 N,N-Dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethylamine benzoate; 2-(5-((1H-1,2,4-triazol-1-yl)methyl)-1H-indol-3-yl)-N,N-dimethylethanamine benzoate

Structure Information of Rizatriptan (benzoate)

Smiles CN(C)CCC1=CNC(C=C2)=C1C=C2CN3C=NC=N3.OC(C4=CC=CC=C4)=O
InChI InChI=1S/C15H19N5.C7H6O2/c1-19(2)6-5-13-8-17-15-4-3-12(7-14(13)15)9-20-11-16-10-18-20;8-7(9)6-4-2-1-3-5-6/h3-4,7-8,10-11,17H,5-6,9H2,1-2H3;1-5H,(H,8,9)

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Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:178-180°C
Boiling point: Flash Point:
Water Solubility: Solubility:
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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