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Chlorpheniramine (maleate)

(CAS: 113-92-8)

Suppliers of Chlorpheniramine (maleate)

Company Name Email Tel Country
AbMole BioScience [email protected] 1-800-660-8580 USA

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AdooQ BioScience, LLC [email protected] 855-GO-ADOOQ (855-462-3667) (US & Canada Toll Free) 866-930-6790 (US & Canada Toll Free) +1-323-389-9269 (Outside of US & Canada) USA

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Apexbio Technology LLC [email protected] +1-832-696-8203 USA

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BOC Sciences [email protected] 1-631-504-6093

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Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

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CHEMSCENE, LLC [email protected] 732-484-9848 USA

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Price and Availability: USD60/1g () USD96/5g ()

Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

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Hubei Hengshuo Chemical Co., Ltd. [email protected] +86 (27) 8283-0253 China

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Jai Radhe Sales [email protected] +91 (79) 2643-1096 India

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LKT Laboratories Inc. [email protected] 1-888-LKT-LABS, 1-888-558-5227 USA

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MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

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Price and Availability: USD60/1g () USD96/5g ()
Quality Control & MSDS Files: HNMR LCMS MSDS

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

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SL Drugs and Pharmaceuticals Pvt. Ltd. [email protected] +91 (40) 6661-1133 India

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Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

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Price and Availability: USD97/50mg (In stock) USD130/10mM/1mLIn DMSO (In stock)
Quality Control & MSDS Files: HNMR HPLC HNMR HPLC

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

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Price and Availability: USD60/1g () USD96/5g ()

Target Molecule Corp. [email protected].com (857) 239-0968 USA

Fax: 857-239-8801Purity: .98 Brand: TargetMol

Price and Availability: USD20/2mg () USD73/10mg () USD135/50mg () USD265/200mg ()

Zhejiang Wonderful Pharma & Chem Co., Ltd. [email protected] +86 (576) 8829-0708 China

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Background Information of Chlorpheniramine (maleate)

Chlorpheniramine maleate is an histamine H1 receptor antagonist with IC50 of 12 nM. Target: Histamine H1 Receptor Chlorpheniramine inhibits the proliferation of MCF-7, MDA-MB 231, and Ehrlich cells in a dose-response manner, and significantly reduces the ornithine decarboxylase mRNA translation by 50%-70% at the 250 μM [1].

Solubility of Chlorpheniramine (maleate)

Solubility Sources
DMSO 80 mg/mL; Water 77 mg/mL MedChemexpress Co., Ltd.
(25°C) * In vitro DMSO 78 mg/mL (199.55 mM); Water78 mg/mL (199.55 mM); Ethanol78 mg/mL (199.55 mM); In vivo Saline20 mg/mL Selleck Chemicals LLC

Storage Condition of Chlorpheniramine (maleate)

Storage Condition Sources

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [LCMS] MedChemexpress Co., Ltd.
[HNMR] [HPLC] Selleck Chemicals LLC

Mechanism and Indications

Signaling Pathways Immunology/Inflammation GPCR/G Protein
Target Histamine Receptor
Research Area Inflammation/Immunology
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Chlorpheniramine (maleate) - Launched

Chemical Information

M.Wt Formula CAS No. Synonyms
390.86 C20H23ClN2O4 113-92-8 Chlorphenamine hydrogen maleate; 1-p-Chlorophenyl-1-(2-pyridyl)-3-dimethylaminopropane maleate; 1-(N,N-Dimethylamino)-3-(p-chlorophenyl)-3-(alpha-pyridyl)propane maleate; 3-(4-chlorophenyl)-N,N-dimethyl-3-(pyridin-2-yl)propan-1-amine maleate

Structure Information of Chlorpheniramine (maleate)

Smiles CN(C)CCC(C1=NC=CC=C1)C2=CC=C(Cl)C=C2.OC(/C=CC(O)=O)=O
InChI InChI=1S/C16H19ClN2.C4H4O4/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13;5-3(6)1-2-4(7)8/h3-9,11,15H,10,12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

Related Products

Other Form Products of Chlorpheniramine (maleate)

Name CAS Formula Suppliers
Chlorpheniramine 132-22-9 C16H19ClN2 3

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Safety Data of Chlorpheniramine (maleate)

Hazard Symbols:T Risk Statements:R25 Safety Statements:S36/37/39;S45
Transport Information:UN 2811 HS Code: RTECS:US6504000
WGK Germany:3

Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:130-135 °C(lit.)
Boiling point: Flash Point:
Water Solubility: 1-5 g/100 mL at 21 ºC Solubility:In vitro:DMSO,78 mg/mL(199.55 mM);In vitro:Water,78 mg/mL(199.55 mM);In vitro:Ethanol,78 mg/mL(199.55 mM);In vivo:Add solvents to the product individually and in order(Data is from Selleck tests instead of citations):SalineFor best results, use promptly a
Density: Merck:2180
BRN: Refractive Index:
Vapour: EINECS:204-037-5
Optical Rotation: alpha: ymsChlorphenamine hydrogen maleate; 1-p-Chlorophenyl-1-(2-pyridyl)-3-dimethylaminopropane maleate; 1-(N,N-Dimethylamino)-3-(p-chlorophenyl)-3-(alpha-pyridyl)propane maleate

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