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Diphenhydramine (hydrochloride)

(CAS: 147-24-0)

Suppliers of Diphenhydramine (hydrochloride)

Company Name Email Tel Country
AdooQ BioScience, LLC [email protected] 855-GO-ADOOQ (855-462-3667) (US & Canada Toll Free) 866-930-6790 (US & Canada Toll Free) +1-323-389-9269 (Outside of US & Canada) USA

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BOC Sciences [email protected] 1-631-504-6093

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Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

Fax: Purity: 0.98 Brand: Biochempartner

CHEMSCENE, LLC [email protected] 732-484-9848 USA

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Price and Availability: USD60/250mg () USD72/500mg ()

Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

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Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

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Choriway International Trade Co., Ltd. [email protected] +86 (510) 8260-6408 China

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Freedom Chemical Supply [email protected] +1 (855) 615-3800 USA

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MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD60/250mg () USD72/500mg ()
Quality Control & MSDS Files: HNMR LCMS MSDS

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

Fax: 919-980-4831Purity: Brand:

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

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Nanjing General Chemical Co., Ltd. [email protected] +86 (25) 8319-0965 China

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Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

Fax: +1-832-582-8590Purity: Brand:

Price and Availability: USD97/50mg (In stock) USD130/10mM/1mLIn DMSO (In stock)
Quality Control & MSDS Files: HNMR HPLC HNMR HPLC

Shanghai Dongyue Biochem Co., Ltd. [email protected] +86 (21) 6410-9415 China

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Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD60/250mg () USD72/500mg ()

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .98 Brand: TargetMol

Price and Availability: USD20/2mg () USD45/10mg () USD78/50mg () USD124/100mg ()

Tocris Bioscience Inc. [email protected]; [email protected] +1 (636) 207-7651 USA

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Wujiang Mingheng Chemical Co., Ltd. [email protected] +86 (512) 6378-6502 / +86 13906258301 China

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Background Information of Diphenhydramine (hydrochloride)

Diphenhydramine HCl (Benadryl), a histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. Target: Histamine H1 receptor Diphenhydramine HCl (Benadryl), a histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations.

Solubility of Diphenhydramine (hydrochloride)

Solubility Sources
DMSO 58 mg/ml MedChemexpress Co., Ltd.
(25°C) * In vitro DMSO 58 mg/mL (198.75 mM); Water58 mg/mL (198.75 mM); Ethanol58 mg/mL (198.75 mM) Selleck Chemicals LLC
Soluble to 100 mM in water Tocris Bioscience Inc.

Storage Condition of Diphenhydramine (hydrochloride)

Storage Condition Sources
Desiccate at RT Tocris Bioscience Inc.

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [LCMS] MedChemexpress Co., Ltd.
[HNMR] [HPLC] Selleck Chemicals LLC

Mechanism and Indications

Signaling Pathways Immunology/Inflammation GPCR/G Protein
Target Histamine Receptor
Research Area Inflammation/Immunology
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Diphenhydramine (hydrochloride) - Launched

Chemical Information

M.Wt Formula CAS No. Synonyms
291.82 C17H22ClNO 147-24-0 Benzhydramine hydrochloride; 2-(Benzhydryloxy)-N,N-dimethylethylamine hydrochloride; N-(2-Diphenylmethoxyethyl)-N,N-dimethylamine hydrochloride; 2-(benzhydryloxy)-N,N-dimethylethanamine hydrochloride

Structure Information of Diphenhydramine (hydrochloride)

Smiles CN(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2.Cl
InChI InChI=1S/C17H21NO.ClH/c1-18(2)13-14-19-17(15-9-5-3-6-10-15)16-11-7-4-8-12-16;/h3-12,17H,13-14H2,1-2H3;1H

Related Products

Other Form Products of Diphenhydramine (hydrochloride)

Name CAS Formula Suppliers
Diphenhydramine 58-73-1 C17H21NO 7

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Safety Data of Diphenhydramine (hydrochloride)

Hazard Symbols:Xn Risk Statements:R22 Safety Statements:36-45-36/37-16-7
Transport Information: HS Code: RTECS:KR7000000
WGK Germany:3

Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:168-172 °C
Boiling point: Flash Point:
Water Solubility: 1000 g/L Solubility:In vitro:DMSO,58 mg/mL(198.75 mM);In vitro:Water,58 mg/mL(198.75 mM);In vitro:Ethanol,58 mg/mL(198.75 mM);
Density: Merck:3309
BRN: Refractive Index:
Vapour: EINECS:205-687-2
Optical Rotation: alpha:

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