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Nizatidine

(CAS: 76963-41-2)

Suppliers of Nizatidine

Company Name Email Tel Country
AbMole BioScience [email protected]le.com 1-800-660-8580 USA

Fax: Purity: Brand:

Apexbio Technology LLC [email protected] +1-832-696-8203 USA

Fax: +1-832-641-3177Purity: Brand:

Ark Pharm, Inc. [email protected] +1 (847) 367-3680 USA

Fax: +1 (847) 367-3681Purity: Brand:

BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: >98% Brand: BOC Sciences

Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

Fax: Purity: 0.98 Brand: Biochempartner

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD66/1g () USD96/5g ()

Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

Fax: (734) 971-3640Purity: Brand:

Changzhou Tigar Fine Chemical Co., Ltd. [email protected] 86 519 515 7016 CHINA

Fax: 86 519 515 7029Purity: Brand:

Guangzhou Winsun Pharmaceutical Co., Ltd. [email protected] +86 (20) 3886-6693 / 3886-6695 China

Fax: +86 (20) 3886-1665Purity: Brand:

Hunan Astar Bio-chemicals Technology Co., Ltd. [email protected] +86 (10) 5831-9740 China

Fax: +86 (10) 5831-9810Purity: Brand:

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD66/1g () USD96/5g ()
Quality Control & MSDS Files: HNMR LCMS

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

Fax: 919-980-4831Purity: Brand:

Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

Fax: +1-832-582-8590Purity: Brand:

Price and Availability: USD97/50mg (In stock)
Quality Control & MSDS Files: HNMR HPLC HNMR HPLC

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD66/1g () USD96/5g ()

Shanghai Pharmarketech Co., Ltd. [email protected],[email protected] +86 (21) 5108-6038 China

Fax: +86 (21) 5108-6038Purity: Brand:

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .99 Brand: TargetMol

Price and Availability: USD20/2mg () USD42/10mg () USD78/50mg () USD122/200mg ()

Wuxi Forest Biological Co., Ltd. [email protected] +86 (510) 8160-2300 China

Fax: +86 (510) 8160-2302Purity: Brand:

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Background Information of Nizatidine

Nizatidine is a histamine H2 receptor antagonist with low toxicity that inhibits gastric acid secretion. Target: Histamine H2 Receptor Nizatidine, a selective histamine H2-receptor antagonist, is a potent inhibitor of gastric acid secretion, with IC50 of 0.9 nM.

Solubility of Nizatidine

Solubility Sources
DMSO 66 mg/mL; Water 30 mg/mL MedChemexpress Co., Ltd.
(25°C) * In vitro DMSO 66 mg/mL (199.11 mM); Water28 mg/mL (84.47 mM); Ethanol18 mg/mL (54.3 mM); In vivo Saline30 mg/mL Selleck Chemicals LLC

Storage Condition of Nizatidine

Storage Condition Sources

MSDS Information

MSDS Sources

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [LCMS] MedChemexpress Co., Ltd.
[HNMR] [HPLC] Selleck Chemicals LLC

Mechanism and Indications

Signaling Pathways Immunology/Inflammation GPCR/G Protein
Target Histamine Receptor
Research Area Inflammation/Immunology
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Nizatidine - Launched

Chemical Information

M.Wt Formula CAS No. Synonyms
331.46 C12H21N5O2S2 76963-41-2 Axid; (E)-N-(2-(((2-((dimethylamino)methyl)thiazol-4-yl)methyl)thio)ethyl)-N-methyl-2-nitroethene-1,1-diamine

Structure Information of Nizatidine

Smiles CN/C(NCCSCC1=CSC(CN(C)C)=N1)=C[N+]([O-])=O
InChI InChI=1S/C12H21N5O2S2/c1-13-11(6-17(18)19)14-4-5-20-8-10-9-21-12(15-10)7-16(2)3/h6,9,13-14H,4-5,7-8H2,1-3H3/b11-6+

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Chemical and Physical Properties

Appearance:Light yellow to yellow Solid Melting point:130-1320C
Boiling point: Flash Point:
Water Solubility: Solubility:In vitro:DMSO,66 mg/mL(199.11 mM);In vitro:Water,28 mg/mL(84.47 mM);In vitro:Ethanol,18 mg/mL(54.3 mM);In vivo:Add solvents to the product individually and in order(Data is from Selleck tests instead of citations):SalineFor best results, use promptly afte
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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