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Trospium (chloride)

(CAS: 10405-02-4)

Suppliers of Trospium (chloride)

Company Name Email Tel Country
Apexbio Technology LLC [email protected] +1-832-696-8203 USA

Fax: +1-832-641-3177Purity: Brand:

Ark Pharm, Inc. [email protected] +1 (847) 367-3680 USA

Fax: +1 (847) 367-3681Purity: Brand:

BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: >98% Brand: BOC Sciences

Beijing Mediking Biopharm Co., Ltd. [email protected],[email protected] +86 (10) 8176-9521 / 8975-3524 China

Fax: +86 (10) 8176-9652Purity: Brand:

Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

Fax: Purity: 0.98 Brand: Biochempartner

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD180/50mg () USD300/100mg ()

Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

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Huaian Synniken Chemical Co., Ltd. [email protected] +86 (10) 8772-7796 / +86 13901024257 China

Fax: +86 (10) 8772-7494Purity: Brand:

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD180/50mg () USD300/100mg ()
Quality Control & MSDS Files: LCMS HNMR MSDS

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

Fax: 919-980-4831Purity: Brand:

Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

Fax: +1-832-582-8590Purity: Brand:

Price and Availability: USD110/25mg (In stock) USD140/10mM/1mLIn DMSO (In stock) USD170/50mg (In stock) USD470/200mg (In stock)
Quality Control & MSDS Files: HNMR HPLC HNMR HPLC

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD180/50mg () USD300/100mg ()

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .99 Brand: TargetMol

Price and Availability: USD37/5mg () USD78/25mg () USD144/50mg ()

Zhejiang Dongdong Pharmaceutical Co., Ltd. [email protected] +86 (576) 8569-8599 China

Fax: Purity: Brand:

Zhejiang Unipharma-Chem Co., Ltd. [email protected],[email protected] +86 (571) 8580-3833 China

Fax: +86 (571) 8580-3855Purity: Brand:

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Background Information of Trospium (chloride)

Trospium Chloride is a competitive muscarinic cholinergic receptor antagonist. Target: mAChR Trospium chloride is an antimuscarinic agent indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and urinary frequency.

Solubility of Trospium (chloride)

Solubility Sources
DMSO 41 mg/mL; Water 85 mg/mL MedChemexpress Co., Ltd.
(25°C) * In vitro DMSO 41 mg/mL (95.8 mM); Water86 mg/mL (200.95 mM); Ethanol42 mg/mL (98.14 mM) Selleck Chemicals LLC

Storage Condition of Trospium (chloride)

Storage Condition Sources

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[LCMS] [HNMR] MedChemexpress Co., Ltd.
[HNMR] [HPLC] Selleck Chemicals LLC

Mechanism and Indications

Signaling Pathways Neuronal Signaling GPCR/G Protein
Target mAChR
Research Area Neurological Disease
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Trospium (chloride) - Launched

Chemical Information

M.Wt Formula CAS No. Synonyms
427.96 C25H30ClNO3 10405-02-4 (1R,3r,5S)-3-(2-hydroxy-2,2-diphenylacetoxy)spiro[bicyclo[3.2.1]octane-8,1'-pyrrolidin]-1'-ium chloride

Structure Information of Trospium (chloride)

Smiles O=C(C(C1=CC=CC=C1)(O)C2=CC=CC=C2)O[[email protected]]3C[[email protected]]4([H])[N+]5(CCCC5)[[email protected]](CC4)([H])C3.[Cl-]
InChI InChI=1S/C25H30NO3.ClH/c27-24(25(28,19-9-3-1-4-10-19)20-11-5-2-6-12-20)29-23-17-21-13-14-22(18-23)26(21)15-7-8-16-26;/h1-6,9-12,21-23,28H,7-8,13-18H2;1H/q+1;/p-1/t21-,22+,23+;

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Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:266-268°C
Boiling point: Flash Point:
Water Solubility: Solubility:In vitro:Water,86 mg/mL(200.95 mM);In vitro:Ethanol,42 mg/mL(98.14 mM);In vitro:DMSO,41 mg/mL(95.8 mM);
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:233-875-4
Optical Rotation: alpha:

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