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Azelastine (hydrochloride)

(CAS: 79307-93-0)

Suppliers of Azelastine (hydrochloride)

Company Name Email Tel Country
AbMole BioScience [email protected] 1-800-660-8580 USA

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AdooQ BioScience, LLC [email protected] 855-GO-ADOOQ (855-462-3667) (US & Canada Toll Free) 866-930-6790 (US & Canada Toll Free) +1-323-389-9269 (Outside of US & Canada) USA

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Alfa Chemistry [email protected] 1-201-478-8534 USA

Fax: 1-516-927-0118Purity: 0.96 Brand: Alfa Chemistry

Apexbio Technology LLC [email protected] +1-832-696-8203 USA

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BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: >98% Brand: BOC Sciences

Price and Availability: USD199/1g (In stock)

Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

Fax: Purity: 0.98 Brand: Biochempartner

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD50/100mg () USD69/200mg ()

Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

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Heta Pharm & Chem Co., Ltd. [email protected],[email protected] +86 (571) 8829-8691 China

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MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD50/100mg () USD69/200mg ()
Quality Control & MSDS Files: LCMS HNMR MSDS

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

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Nanjing Samwon International Limited [email protected],[email protected] +86 (25) 8487-3444 China

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Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

Fax: +1-832-582-8590Purity: Brand:

Price and Availability: USD50/100mg (In stock) USD70/10mM/1mLIn DMSO (In stock)
Quality Control & MSDS Files: HNMR HPLC HNMR HPLC

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD50/100mg () USD69/200mg ()

Shanghai Jinhuan Chemical Co., Ltd. [email protected] +86 (21) 6142-0008 China

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Shanghai Luer Chemical Trading Co., Ltd [email protected] 0086-21-68739752 CHINA

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Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .98 Brand: TargetMol

Price and Availability: USD20/2mg () USD75/10mg () USD268/50mg ()

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Background Information of Azelastine (hydrochloride)

Azelastine HCl is a potent, second-generation, selective, histamine antagonist. Target: Histamine Receptor Azelastine is a selective H(1)-receptor antagonist that inhibits histamine release and interferes with activation of several other mediators of allergic inflammation.

Solubility of Azelastine (hydrochloride)

Solubility Sources
DMSO 85 mg/mL; Water 35 mg/mL MedChemexpress Co., Ltd.
(25°C) * In vitro DMSO 84 mg/mL (200.78 mM); Ethanol84 mg/mL (200.78 mM); Water35 mg/mL (83.66 mM) Selleck Chemicals LLC

Storage Condition of Azelastine (hydrochloride)

Storage Condition Sources

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[LCMS] [HNMR] MedChemexpress Co., Ltd.
[HNMR] [HPLC] Selleck Chemicals LLC

Mechanism and Indications

Signaling Pathways Immunology/Inflammation GPCR/G Protein
Target Histamine Receptor
Research Area Inflammation/Immunology
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Azelastine (hydrochloride) - Launched

Chemical Information

M.Wt Formula CAS No. Synonyms
418.36 C22H25Cl2N3O 79307-93-0 Astelin;Optivar;Allergodil;Rhinolast;Optilas; 4-(4-chlorobenzyl)-2-(1-methylazepan-4-yl)phthalazin-1(2H)-one hydrochloride

Structure Information of Azelastine (hydrochloride)

Smiles O=C1N(C2CCN(C)CCC2)N=C(CC3=CC=C(Cl)C=C3)C4=C1C=CC=C4.Cl
InChI InChI=1S/C22H24ClN3O.ClH/c1-25-13-4-5-18(12-14-25)26-22(27)20-7-3-2-6-19(20)21(24-26)15-16-8-10-17(23)11-9-16;/h2-3,6-11,18H,4-5,12-15H2,1H3;1H

Related Products

Other Form Products of Azelastine (hydrochloride)

Name CAS Formula Suppliers
Azelastine 58581-89-8 C22H24ClN3O 12

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Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:225--2290C
Boiling point: Flash Point:
Water Solubility: Solubility:In vitro:Ethanol,42 mg/mL(100.39 mM);In vitro:Water,35 mg/mL(83.66 mM);In vitro:DMSO,28 mg/mL(66.92 mM);
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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