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Ebastine

(CAS: 90729-43-4)

Suppliers of Ebastine

Company Name Email Tel Country
AA Blocks LLC [email protected] +1 858-523-8231

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AbMole BioScience [email protected] 1-800-660-8580 USA

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AdooQ BioScience, LLC [email protected] 855-GO-ADOOQ (855-462-3667) (US & Canada Toll Free) 866-930-6790 (US & Canada Toll Free) +1-323-389-9269 (Outside of US & Canada) USA

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Ark Pharm, Inc. [email protected] +1 (847) 367-3680 USA

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BLD Pharmatech [email protected] +86-21-61629022

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BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: >98% Brand: BOC Sciences

Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

Fax: Purity: 0.98 Brand: Biochempartner

CHEMSCENE, LLC [email protected] 732-484-9848 USA

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Price and Availability: USD60/500mg () USD84/1g ()

Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

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Jiangsu Allyrise Pharmaceutical Co., Ltd. [email protected] +86 (523) 8681-8997 / +86 18651171855 China

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MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD60/500mg () USD84/1g ()
Quality Control & MSDS Files: HNMR LCMS MSDS

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

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Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

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Price and Availability: USD97/50mg (In stock)
Quality Control & MSDS Files: HPLC HPLC

Shanghai Hanjing Chemicals Co., Ltd. [email protected],[email protected] +86 (21) 3700-9251 / 3700-9252 China

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Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

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Price and Availability: USD60/500mg () USD84/1g ()

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .98 Brand: TargetMol

Price and Availability: USD36/2mg () USD85/10mg () USD168/50mg ()

Yangzhou Lianhuan Pharmaceutical Co., Ltd. [email protected] +86 (514) 8782-9985 China

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Zhejiang Wonderful Pharma & Chem Co., Ltd. [email protected] +86 (576) 8829-0708 China

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Background Information of Ebastine

Ebastine(LAS-W 090;RP64305) is a long-acting and selective H1-histamine receptor antagonist. Target: Histamine H1 Receptor Ebastine is a H1 antihistamine with low potential for causing drowsiness.

Solubility of Ebastine

Solubility Sources
DMSO 2 mg/mL; Water <1 mg/mL MedChemexpress Co., Ltd.
(25°C) * In vitro DMSO 2 mg/mL (4.25 mM); Ethanol11 mg/mL (23.42 mM); Water<1 mg/mL (<1 mM) Selleck Chemicals LLC

Storage Condition of Ebastine

Storage Condition Sources

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [LCMS] MedChemexpress Co., Ltd.
[HPLC] Selleck Chemicals LLC

Mechanism and Indications

Signaling Pathways Immunology/Inflammation GPCR/G Protein
Target Histamine Receptor
Research Area Inflammation/Immunology
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Ebastine - Launched
Ebastine - Phase 4

Chemical Information

M.Wt Formula CAS No. Synonyms
469.66 C32H39NO2 90729-43-4 LAS-W 090;RP64305; 4-(4-(benzhydryloxy)piperidin-1-yl)-1-(4-(tert-butyl)phenyl)butan-1-one

Structure Information of Ebastine

Smiles O=C(C1=CC=C(C(C)(C)C)C=C1)CCCN2CCC(OC(C3=CC=CC=C3)C4=CC=CC=C4)CC2
InChI InChI=1S/C32H39NO2/c1-32(2,3)28-18-16-25(17-19-28)30(34)15-10-22-33-23-20-29(21-24-33)35-31(26-11-6-4-7-12-26)27-13-8-5-9-14-27/h4-9,11-14,16-19,29,31H,10,15,20-24H2,1-3H3

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Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:80-82°C
Boiling point: Flash Point:
Water Solubility: Solubility:In vitro:Ethanol,11 mg/mL(23.42 mM);In vitro:DMSO,4 mg/mLwarmed(8.51 mM);In vitro:Water,Insoluble;
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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